Preventive effects of rutin on lysosomal enzymes in isoproterenol induced cardio toxic rats: Biochemical, histological and in vitro evidences

This study was aimed to evaluate the preventive effect of rutin on lysosomal enzymes in isoproterenol induced cardio toxic rats. Male albino Wistar rats were pretreated with rutin (80 mg/kg) daily for a period of 42 days. After the pretreatment period, isoproterenol (100 mg/kg) was subcutaneously in...

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Veröffentlicht in:	European journal of pharmacology 2010-12, Vol.649 (1), p.229-235
Hauptverfasser:	Stanely Mainzen Prince, Ponnian, Priya, Shanmuga
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - chemistry Antioxidants - pharmacology Antioxidants - therapeutic use Biological and medical sciences Biomarkers - blood Cardiology. Vascular system Cardiotonic Agents - chemistry Cardiotonic Agents - pharmacology Cardiotonic Agents - therapeutic use Cardiotoxins - toxicity Coronary heart disease Creatine Kinase, MB Form - blood Heart Heart - drug effects Histopathology Intracellular Membranes - drug effects Intracellular Membranes - enzymology Isoproterenol Isoproterenol - toxicity Lysosomal enzymes Lysosomes - drug effects Lysosomes - enzymology Male Medical sciences Myocardial infarction Myocardial Reperfusion Injury - blood Myocardial Reperfusion Injury - enzymology Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - prevention & control Myocarditis. Cardiomyopathies Myocardium - enzymology Myocardium - pathology Pharmacology. Drug treatments Rats Rats, Wistar Rutin Rutin - chemistry Rutin - pharmacology Rutin - therapeutic use Severity of Illness Index Subcellular Fractions - drug effects Subcellular Fractions - enzymology Troponin I - blood Troponin T - blood
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