Construction and Characterization of a Recombinant Canine Adenovirus Expressing GP5 and M proteins of Porcine Reproductive and Respiratory Syndrome Virus

The causative agent of porcine reproductive and respiratory syndrome (PRRS) is PRRS virus (PRRSV), which belongs to the family Arteriviridae. GP5/M protein complex of PRRSV binds to sialoadhesion expressed on the cells to infect the cells. In this study, we developed a canine adenovirus type 2 (CAV-...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2010, Vol.72(8), pp.1035-1040
Hauptverfasser:	CAI, Jinshun, MA, Yonghe, LI, Jiaying, YAN, Changguo, HU, Rongliang, ZHANG, Jiabao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Adenoviruses, Canine - genetics Animals Arterivirus Infections - genetics Arterivirus Infections - immunology Arterivirus Infections - veterinary Cell Line DNA Primers Dog Diseases - genetics Dog Diseases - virology Dogs GP5 Immunization - methods Immunization - veterinary immunogenicity Kidney - virology Macaca mulatta Neutralization Tests Plasmids - genetics Polymerase Chain Reaction porcine reproductive and respiratory syndrome virus Porcine respiratory and reproductive syndrome virus Porcine respiratory and reproductive syndrome virus - genetics recombinant canine adenovirus Recombination, Genetic Restriction Mapping Viral Envelope Proteins - genetics Viral Matrix Proteins - genetics
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