Dynamic antibody responses to the Mycobacterium tuberculosis proteome

Considerable effort has been directed toward controlling tuberculosis, which kills almost two million people yearly. High on the research agenda is the discovery of biomarkers of active tuberculosis (TB) for diagnosis and for monitoring treatment outcome. Rational biomarker discovery requires unders...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-08, Vol.107 (33), p.14703-14708
Hauptverfasser:	Kunnath-Velayudhan, Shajo, Salamon, Hugh, Wang, Hui-Yun, Davidow, Amy L., Molina, Douglas M., Huynh, Vu T., Cirillo, Daniela M., Michel, Gerd, Talbot, Elizabeth A., Perkins, Mark D., Felgner, Philip L., Liang, Xiaowu, Gennaro, Maria L., Rappuoli, Rino
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Bacterial - blood Antibodies, Bacterial - immunology Antibody formation Antibody Formation - immunology Antigens Antigens, Bacterial - blood Antigens, Bacterial - immunology Bacterial Proteins - analysis Bacterial Proteins - immunology Bacteriology Biological Sciences Biomarkers Cells Chronic infection Data processing Evolution Granuloma Host-pathogen interactions Host-Pathogen Interactions - immunology Humans Immunology Infections Lung Lymphocytes B Mycobacterium tuberculosis Mycobacterium tuberculosis - immunology Mycobacterium tuberculosis - metabolism Mycobacterium tuberculosis - physiology Pathogens Proteins Proteome - analysis Proteome - immunology Proteomes Proteomics Reactivity Tuberculosis Tuberculosis - blood Tuberculosis - immunology Tuberculosis - microbiology Tuberculosis vaccine
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