Modeling and simulation of cephalosporin C production in a fed-batch tower-type bioreactor

Immobilized cell utilization in tower-type bioreactor is one of the main alternatives being studied to improve the industrial bioprocess. Other alternatives for the production of beta-lactam antibiotics, such as a cephalosporin C fed-batch process in an aerated stirred-tankbioreactor with free cells...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2001, Vol.91-93 (1-9), p.537-549
Hauptverfasser:	ALMEIDA, Renata M. R. G, CRUZ, Antonio J. G, ARAUJO, Maria Lucia G. C, GIORDANO, Roberto C, HOKKA, Carlos O
Format:	Artikel
Sprache:	eng
Schlagworte:	Acremonium - growth & development Acremonium - metabolism Antibiotics Biological and medical sciences Biomass Bioreactors Biotechnology Carbon sources Cells, Immobilized Cephalosporins - biosynthesis Cephalosporium acremonium Confidence intervals Culture Media Differential equations Dissolved oxygen Equipment Design Experimental data Flow rates Fundamental and applied biological sciences. Psychology Glucose - metabolism Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Kinetics Mathematical models Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology Models, Biological Production of active biomolecules Studies Sucrose - metabolism
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