Effects of zinc deficiency and supplementation on plasma leptin levels in rats
The effects of zinc deficiency and supplementation on plasma leptin levels were studied in Sprague-Dawley rats. After 6 wk on a zinc-deficient diet containing 0.65 ppm Zn/g, the mean body weight was significantly lower than that of normal or zinc-supplemented rats, which showed no difference among t...
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| Veröffentlicht in: | Biological trace element research 2005-04, Vol.104 (1), p.41-46 |
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| creator | Baltaci, Abdulkerim Kasim Mogulkoc, Rasim Halifeoglu, Ihsan |
| description | The effects of zinc deficiency and supplementation on plasma leptin levels were studied in Sprague-Dawley rats. After 6 wk on a zinc-deficient diet containing 0.65 ppm Zn/g, the mean body weight was significantly lower than that of normal or zinc-supplemented rats, which showed no difference among them. The plasma leptin and zinc levels were lowest in zinc-deficient animals and highest in those that received a normal diet and daily intraperitioneal injections of 3 mg Zn/kg. These results indicate that zinc deficiency leads to a significant inhibition in plasma leptin levels, whereas zinc supplementation significantly increases plasma leptin. |
| doi_str_mv | 10.1385/BTER:104:1:041 |
| format | Article |
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| subjects | Animals Body weight Body Weight - drug effects Diet Leptin - blood Male Nutrition Plasma Rats Rats, Sprague-Dawley Rodents Zinc Zinc - blood Zinc - deficiency Zinc - pharmacology |
| title | Effects of zinc deficiency and supplementation on plasma leptin levels in rats |
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