Detection of metallo-b-lactamase-encoding genes among clinical isolates of Pseudomonas aeruginosa in northwest of Iran

The prevalence of metallo-b-lactamase (MBL) production among 104 clinical isolates of Pseudomonas aeruginosa from northwest of Iran was investigated by phenotypic and polymerase chain reaction (PCR) methods. Thirty-nine (37.50%) of isolates were MBL positive by double-disk synergy test. Results of P...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 2010-11, Vol.68 (3), p.322-325
Hauptverfasser: Yousefi, Saber, Farajnia, Safar, Nahaei, Mohammd Reza, Akhi, Mohammad Taghi, Ghotaslou, Reza, Soroush, Mohammad Hossein, Naghili, Behrooz, Jazani, Nima Hosseini
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container_issue 3
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container_title Diagnostic microbiology and infectious disease
container_volume 68
creator Yousefi, Saber
Farajnia, Safar
Nahaei, Mohammd Reza
Akhi, Mohammad Taghi
Ghotaslou, Reza
Soroush, Mohammad Hossein
Naghili, Behrooz
Jazani, Nima Hosseini
description The prevalence of metallo-b-lactamase (MBL) production among 104 clinical isolates of Pseudomonas aeruginosa from northwest of Iran was investigated by phenotypic and polymerase chain reaction (PCR) methods. Thirty-nine (37.50%) of isolates were MBL positive by double-disk synergy test. Results of PCR revealed that 18 (17.31%) and 6 (5.77%) imipenem nonsusceptible isolates of P. aeruginosa carried bla VIM and bla IMP genes respectively, while 92.4% (62/67) of isolates contained class 1 integron gene. This is the first report of MBL-producing P. aeruginosa from northwest of Iran.
doi_str_mv 10.1016/j.diagmicrobio.2010.06.018
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title Detection of metallo-b-lactamase-encoding genes among clinical isolates of Pseudomonas aeruginosa in northwest of Iran
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