Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia
In order to evaluate serum copper and zinc status in children with iron deficiency anemia (IDA), 60 children with IDA aged 1-14 yr and 64 healthy children as controls aged 1-14 yr were included the study. Serum copper levels were higher in children with IDA (189 +/- 49 micrograms/dL) than those of c...
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| Veröffentlicht in: | Biological trace element research 1997-12, Vol.59 (1/3), p.31-39 |
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| creator | Ece, A Uyanik, B.S Iscan, A Ertan, P Yigitoglu, M.R |
| description | In order to evaluate serum copper and zinc status in children with iron deficiency anemia (IDA), 60 children with IDA aged 1-14 yr and 64 healthy children as controls aged 1-14 yr were included the study. Serum copper levels were higher in children with IDA (189 +/- 49 micrograms/dL) than those of controls (163 +/- 37 micrograms/dL) (p = 0.001). Serum zinc levels were lower in the patient group (109 +/- 59 micrograms/dL) than those of control subjects (135 +/- 56 micrograms/dL) (p = 0.017). In addition, there were statistically significant negative correlations between hematological parameters and serum copper levels in the patient group, but not in controls. No correlation between hematological parameters and serum zinc levels were found in both patient and control groups, except positive correlation between mean corpuscular volume (MCV) and serum zinc level in patients. It was concluded that at the time of managing children with IDA, zinc deficiency must be borne in mind and if necessary treatment should be initiated with zinc. |
| doi_str_mv | 10.1007/BF02783227 |
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Serum copper levels were higher in children with IDA (189 +/- 49 micrograms/dL) than those of controls (163 +/- 37 micrograms/dL) (p = 0.001). Serum zinc levels were lower in the patient group (109 +/- 59 micrograms/dL) than those of control subjects (135 +/- 56 micrograms/dL) (p = 0.017). In addition, there were statistically significant negative correlations between hematological parameters and serum copper levels in the patient group, but not in controls. No correlation between hematological parameters and serum zinc levels were found in both patient and control groups, except positive correlation between mean corpuscular volume (MCV) and serum zinc level in patients. It was concluded that at the time of managing children with IDA, zinc deficiency must be borne in mind and if necessary treatment should be initiated with zinc.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/BF02783227</identifier><identifier>PMID: 9522044</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Adolescent ; Anaemia ; Anemia ; Anemia, Iron-Deficiency - blood ; BLOOD ; BLOOD SERUM ; CARENCE EN SUBSTANCE NUTRITIVE ; Child ; Child, Preschool ; Children ; Copper ; Copper - blood ; Correlation ; DEFICIENCIAS NUTRITIVAS ; Female ; HEMATOLOGY ; Humans ; Infant ; Iron ; Iron deficiency ; Male ; NUTRIENT DEFICIENCIES ; Nutrient deficiency ; Nutrition ; Parameters ; SANG ; SANGRE ; Serum ; SERUM SANGUIN ; Statistical analysis ; SUERO SANGUINEO ; Zinc ; Zinc - blood</subject><ispartof>Biological trace element research, 1997-12, Vol.59 (1/3), p.31-39</ispartof><rights>Humana Press Inc. 1997</rights><rights>Humana Press Inc. 1997.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-5d3257b1fc8148be3fdc0788cd65e16c458849b44ab304f1ce44cf977a79b1e93</citedby><cites>FETCH-LOGICAL-c391t-5d3257b1fc8148be3fdc0788cd65e16c458849b44ab304f1ce44cf977a79b1e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9522044$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ece, A</creatorcontrib><creatorcontrib>Uyanik, B.S</creatorcontrib><creatorcontrib>Iscan, A</creatorcontrib><creatorcontrib>Ertan, P</creatorcontrib><creatorcontrib>Yigitoglu, M.R</creatorcontrib><title>Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><description>In order to evaluate serum copper and zinc status in children with iron deficiency anemia (IDA), 60 children with IDA aged 1-14 yr and 64 healthy children as controls aged 1-14 yr were included the study. Serum copper levels were higher in children with IDA (189 +/- 49 micrograms/dL) than those of controls (163 +/- 37 micrograms/dL) (p = 0.001). Serum zinc levels were lower in the patient group (109 +/- 59 micrograms/dL) than those of control subjects (135 +/- 56 micrograms/dL) (p = 0.017). In addition, there were statistically significant negative correlations between hematological parameters and serum copper levels in the patient group, but not in controls. No correlation between hematological parameters and serum zinc levels were found in both patient and control groups, except positive correlation between mean corpuscular volume (MCV) and serum zinc level in patients. It was concluded that at the time of managing children with IDA, zinc deficiency must be borne in mind and if necessary treatment should be initiated with zinc.</description><subject>Adolescent</subject><subject>Anaemia</subject><subject>Anemia</subject><subject>Anemia, Iron-Deficiency - blood</subject><subject>BLOOD</subject><subject>BLOOD SERUM</subject><subject>CARENCE EN SUBSTANCE NUTRITIVE</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Copper</subject><subject>Copper - blood</subject><subject>Correlation</subject><subject>DEFICIENCIAS NUTRITIVAS</subject><subject>Female</subject><subject>HEMATOLOGY</subject><subject>Humans</subject><subject>Infant</subject><subject>Iron</subject><subject>Iron deficiency</subject><subject>Male</subject><subject>NUTRIENT DEFICIENCIES</subject><subject>Nutrient deficiency</subject><subject>Nutrition</subject><subject>Parameters</subject><subject>SANG</subject><subject>SANGRE</subject><subject>Serum</subject><subject>SERUM SANGUIN</subject><subject>Statistical analysis</subject><subject>SUERO SANGUINEO</subject><subject>Zinc</subject><subject>Zinc - 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Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ece, A</au><au>Uyanik, B.S</au><au>Iscan, A</au><au>Ertan, P</au><au>Yigitoglu, M.R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia</atitle><jtitle>Biological trace element research</jtitle><addtitle>Biol Trace Elem Res</addtitle><date>1997-12-01</date><risdate>1997</risdate><volume>59</volume><issue>1/3</issue><spage>31</spage><epage>39</epage><pages>31-39</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>In order to evaluate serum copper and zinc status in children with iron deficiency anemia (IDA), 60 children with IDA aged 1-14 yr and 64 healthy children as controls aged 1-14 yr were included the study. Serum copper levels were higher in children with IDA (189 +/- 49 micrograms/dL) than those of controls (163 +/- 37 micrograms/dL) (p = 0.001). Serum zinc levels were lower in the patient group (109 +/- 59 micrograms/dL) than those of control subjects (135 +/- 56 micrograms/dL) (p = 0.017). In addition, there were statistically significant negative correlations between hematological parameters and serum copper levels in the patient group, but not in controls. No correlation between hematological parameters and serum zinc levels were found in both patient and control groups, except positive correlation between mean corpuscular volume (MCV) and serum zinc level in patients. It was concluded that at the time of managing children with IDA, zinc deficiency must be borne in mind and if necessary treatment should be initiated with zinc.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>9522044</pmid><doi>10.1007/BF02783227</doi><tpages>9</tpages></addata></record> |
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| ispartof | Biological trace element research, 1997-12, Vol.59 (1/3), p.31-39 |
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| subjects | Adolescent Anaemia Anemia Anemia, Iron-Deficiency - blood BLOOD BLOOD SERUM CARENCE EN SUBSTANCE NUTRITIVE Child Child, Preschool Children Copper Copper - blood Correlation DEFICIENCIAS NUTRITIVAS Female HEMATOLOGY Humans Infant Iron Iron deficiency Male NUTRIENT DEFICIENCIES Nutrient deficiency Nutrition Parameters SANG SANGRE Serum SERUM SANGUIN Statistical analysis SUERO SANGUINEO Zinc Zinc - blood |
| title | Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia |
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