Leukocyte reactivity as an objective means of quantifying mental loading during ergonomic evaluation
Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 a...
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| Veröffentlicht in: | Cellular immunology 2010, Vol.263 (1), p.22-30 |
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| creator | Shelton-Rayner, G.K. Macdonald, D.W. Chandler, S. Robertson, D. Mian, R. |
| description | Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56
years) provided capillary blood samples before and after completing three basic tasks using, in turn, two automotive touch screen interfaces (Interface 1—antecedent version, Interface 2—improved version). Using a chemiluminescent technique termed leukocyte coping capacity (LCC), the ability of leukocytes to produce reactive oxygen species
in vitro was assessed. Significant differences in leukocyte activity were shown between treatment groups, where the greatest post-test decrease occurred after using Interface 1. Phase 2: a randomly selected sub-group (
n
=
4) underwent weekly repeat testing using both interfaces. Significant differences in post-test leukocyte reactivity were exhibited between test weeks for each interface—the magnitude of response decreasing with successive exposure. |
| doi_str_mv | 10.1016/j.cellimm.2010.02.011 |
| format | Article |
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years) provided capillary blood samples before and after completing three basic tasks using, in turn, two automotive touch screen interfaces (Interface 1—antecedent version, Interface 2—improved version). Using a chemiluminescent technique termed leukocyte coping capacity (LCC), the ability of leukocytes to produce reactive oxygen species
in vitro was assessed. Significant differences in leukocyte activity were shown between treatment groups, where the greatest post-test decrease occurred after using Interface 1. Phase 2: a randomly selected sub-group (
n
=
4) underwent weekly repeat testing using both interfaces. Significant differences in post-test leukocyte reactivity were exhibited between test weeks for each interface—the magnitude of response decreasing with successive exposure.</description><identifier>ISSN: 0008-8749</identifier><identifier>EISSN: 1090-2163</identifier><identifier>DOI: 10.1016/j.cellimm.2010.02.011</identifier><identifier>PMID: 20299010</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adaptation, Psychological ; Adult ; Blood Pressure ; Body Temperature ; Chemiluminescence ; Ergonomics - psychology ; Feasibility Studies ; Female ; Habituation ; Heart Rate ; Humans ; Immune system ; Leukocytes ; Leukocytes, Mononuclear - pathology ; Leukocytes, Mononuclear - physiology ; Luminol ; Male ; Mental workload ; Middle Aged ; Neutrophils ; Psychological stress ; Psychological Tests ; Reactive oxygen species ; Reactive Oxygen Species - immunology ; Reactive Oxygen Species - metabolism ; Stress, Psychological - blood ; Stress, Psychological - diagnosis ; Stress, Psychological - immunology</subject><ispartof>Cellular immunology, 2010, Vol.263 (1), p.22-30</ispartof><rights>2010 Elsevier Inc.</rights><rights>Copyright 2010 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-8eaf5bb4df1fc517a5d5cd57f565c9d1074c6e323b0def4ce6231d51562583403</citedby><cites>FETCH-LOGICAL-c443t-8eaf5bb4df1fc517a5d5cd57f565c9d1074c6e323b0def4ce6231d51562583403</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0008874910000419$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,4009,27902,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20299010$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shelton-Rayner, G.K.</creatorcontrib><creatorcontrib>Macdonald, D.W.</creatorcontrib><creatorcontrib>Chandler, S.</creatorcontrib><creatorcontrib>Robertson, D.</creatorcontrib><creatorcontrib>Mian, R.</creatorcontrib><title>Leukocyte reactivity as an objective means of quantifying mental loading during ergonomic evaluation</title><title>Cellular immunology</title><addtitle>Cell Immunol</addtitle><description>Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56
years) provided capillary blood samples before and after completing three basic tasks using, in turn, two automotive touch screen interfaces (Interface 1—antecedent version, Interface 2—improved version). Using a chemiluminescent technique termed leukocyte coping capacity (LCC), the ability of leukocytes to produce reactive oxygen species
in vitro was assessed. Significant differences in leukocyte activity were shown between treatment groups, where the greatest post-test decrease occurred after using Interface 1. Phase 2: a randomly selected sub-group (
n
=
4) underwent weekly repeat testing using both interfaces. Significant differences in post-test leukocyte reactivity were exhibited between test weeks for each interface—the magnitude of response decreasing with successive exposure.</description><subject>Adaptation, Psychological</subject><subject>Adult</subject><subject>Blood Pressure</subject><subject>Body Temperature</subject><subject>Chemiluminescence</subject><subject>Ergonomics - psychology</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Habituation</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Immune system</subject><subject>Leukocytes</subject><subject>Leukocytes, Mononuclear - pathology</subject><subject>Leukocytes, Mononuclear - physiology</subject><subject>Luminol</subject><subject>Male</subject><subject>Mental workload</subject><subject>Middle Aged</subject><subject>Neutrophils</subject><subject>Psychological stress</subject><subject>Psychological Tests</subject><subject>Reactive oxygen species</subject><subject>Reactive Oxygen Species - immunology</subject><subject>Reactive Oxygen Species - metabolism</subject><subject>Stress, Psychological - blood</subject><subject>Stress, Psychological - diagnosis</subject><subject>Stress, Psychological - immunology</subject><issn>0008-8749</issn><issn>1090-2163</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9r3DAQxUVJaTZpP0KDbjl5M5Is_zmVEtI2sJBLexayNAra2lIi2Qv77Suzm15zGubxezPwHiFfGWwZsOZuvzU4jn6athyKBnwLjH0gGwY9VJw14oJsAKCrurbuL8lVznsoRN3DJ3LJgfd9sW2I3eHyN5rjjDShNrM_-PlIdaY60DjscVWQTqhDptHR10WH2bujD89FDLMe6Ri1XVe7pHVgeo4hTt5QPOhx0bOP4TP56PSY8ct5XpM_Px5-3_-qdk8_H--_7ypT12KuOtRODkNtHXNGslZLK42VrZONNL1l0NamQcHFABZdbbDhglnJZMNlJ2oQ1-T2dPclxdcF86wmn9eYdMC4ZNUxKQVvG_Eu2QrRi7YHXkh5Ik2KOSd06iX5SaejYqDWJtRenZtQaxMKuCo5F9_N-cMyTGj_u96iL8C3E4AlkYPHpLLxGAxan0rsykb_zot_l6CeDA</recordid><startdate>2010</startdate><enddate>2010</enddate><creator>Shelton-Rayner, G.K.</creator><creator>Macdonald, D.W.</creator><creator>Chandler, S.</creator><creator>Robertson, D.</creator><creator>Mian, R.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>2010</creationdate><title>Leukocyte reactivity as an objective means of quantifying mental loading during ergonomic evaluation</title><author>Shelton-Rayner, G.K. ; 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This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56
years) provided capillary blood samples before and after completing three basic tasks using, in turn, two automotive touch screen interfaces (Interface 1—antecedent version, Interface 2—improved version). Using a chemiluminescent technique termed leukocyte coping capacity (LCC), the ability of leukocytes to produce reactive oxygen species
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n
=
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adaptation, Psychological Adult Blood Pressure Body Temperature Chemiluminescence Ergonomics - psychology Feasibility Studies Female Habituation Heart Rate Humans Immune system Leukocytes Leukocytes, Mononuclear - pathology Leukocytes, Mononuclear - physiology Luminol Male Mental workload Middle Aged Neutrophils Psychological stress Psychological Tests Reactive oxygen species Reactive Oxygen Species - immunology Reactive Oxygen Species - metabolism Stress, Psychological - blood Stress, Psychological - diagnosis Stress, Psychological - immunology |
| title | Leukocyte reactivity as an objective means of quantifying mental loading during ergonomic evaluation |
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