Origin of glycine from acid hydrolysis of the -lactam antibiotic A16886B

Structural analysis of two new beta-lactam antibiotics, A16884A and A16886B, indicated that they, like cephalosporin C, were composed of modified valine and cysteine residues, and alpha-aminoadipic acid. However, acid hydrolysis of A16886B and A16884A produced three times as much glycine as did hydr...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 1972-03, Vol.1 (3), p.242-246
Hauptverfasser:	Brannon, D R, Mabe, J A, Ellis, R, Whitney, J G, Nagarajan, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbamates Carbon Isotopes Cephalosporins - isolation & purification Chromatography, Paper Decarboxylation Glycine - chemical synthesis Hydrolysis Indicators and Reagents Methyl Ethers Streptomyces
Online-Zugang:	Volltext
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