Attenuated Marek's disease herpesvirus: Protection conferred on strains of chickens varying in genetic resistance
Five strains of chickens differing in susceptibility to Marek's disease (MD) were vaccinated with the attenuated BC-1 isolate of MD herpesvirus and were subsequently challenged with virulent virus. Significant protection was conferred to all strains. However, when vaccination was at 1 or 2 days...
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| Veröffentlicht in: | Avian diseases 1972-04, Vol.16 (1), p.94-107 |
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| container_end_page | 107 |
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| container_title | Avian diseases |
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| creator | Spencer, J.L Grunder, A.A Robertson, A Speckmann, G.W |
| description | Five strains of chickens differing in susceptibility to Marek's disease (MD) were vaccinated with the attenuated BC-1 isolate of MD herpesvirus and were subsequently challenged with virulent virus. Significant protection was conferred to all strains. However, when vaccination was at 1 or 2 days there were significant differences among strains in the incidence of gross lesions of MD. The ranking of strains for susceptibility to MD was not usually altered by vaccination. By comparison, differences in the susceptibility of strains was not observed among chickens vaccinated at 23 days and these were better protected than those vaccinated at 2 days. Vaccination at both 2 and 23 days showed no significant advantage over a single vaccination at 23 days. |
| doi_str_mv | 10.2307/1588904 |
| format | Article |
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Significant protection was conferred to all strains. However, when vaccination was at 1 or 2 days there were significant differences among strains in the incidence of gross lesions of MD. The ranking of strains for susceptibility to MD was not usually altered by vaccination. By comparison, differences in the susceptibility of strains was not observed among chickens vaccinated at 23 days and these were better protected than those vaccinated at 2 days. Vaccination at both 2 and 23 days showed no significant advantage over a single vaccination at 23 days.</description><identifier>ISSN: 0005-2086</identifier><identifier>EISSN: 1938-4351</identifier><identifier>DOI: 10.2307/1588904</identifier><identifier>PMID: 4337320</identifier><language>eng</language><publisher>United States: American Association of Avian Pathologists, Inc</publisher><subject>Age Factors ; animal diseases ; animal health ; Animals ; Antibodies ; Antigens, Viral ; Avian Leukosis - immunology ; Cell culture techniques ; Chickens - immunology ; Female ; Gallid herpesvirus 2 ; Genetics, Population ; Herpesviridae ; Herpesviridae - immunology ; Herpesviridae - pathogenicity ; Herpesviridae Infections - veterinary ; Housing, Animal ; Injections ; Lesions ; Male ; Marek Disease - genetics ; Marek Disease - immunology ; Marek Disease - mortality ; Marek Disease - pathology ; Marek Disease - prevention & control ; Mortality ; Poultry Diseases - immunology ; Transcriptional regulatory elements ; Vaccination ; Vaccination - veterinary ; Viral diseases ; Viral Vaccines - administration & dosage ; Virulence ; Viruses</subject><ispartof>Avian diseases, 1972-04, Vol.16 (1), p.94-107</ispartof><rights>Copyright 1972 The American Association of Avian Pathologists, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c244t-688d8545c03d3561f75e0ab648875923c2aabf20567571feaec8bb0d8994dc543</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1588904$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1588904$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27923,27924,58016,58249</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4337320$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spencer, J.L</creatorcontrib><creatorcontrib>Grunder, A.A</creatorcontrib><creatorcontrib>Robertson, A</creatorcontrib><creatorcontrib>Speckmann, G.W</creatorcontrib><title>Attenuated Marek's disease herpesvirus: Protection conferred on strains of chickens varying in genetic resistance</title><title>Avian diseases</title><addtitle>Avian Dis</addtitle><description>Five strains of chickens differing in susceptibility to Marek's disease (MD) were vaccinated with the attenuated BC-1 isolate of MD herpesvirus and were subsequently challenged with virulent virus. Significant protection was conferred to all strains. However, when vaccination was at 1 or 2 days there were significant differences among strains in the incidence of gross lesions of MD. The ranking of strains for susceptibility to MD was not usually altered by vaccination. By comparison, differences in the susceptibility of strains was not observed among chickens vaccinated at 23 days and these were better protected than those vaccinated at 2 days. Vaccination at both 2 and 23 days showed no significant advantage over a single vaccination at 23 days.</description><subject>Age Factors</subject><subject>animal diseases</subject><subject>animal health</subject><subject>Animals</subject><subject>Antibodies</subject><subject>Antigens, Viral</subject><subject>Avian Leukosis - immunology</subject><subject>Cell culture techniques</subject><subject>Chickens - immunology</subject><subject>Female</subject><subject>Gallid herpesvirus 2</subject><subject>Genetics, Population</subject><subject>Herpesviridae</subject><subject>Herpesviridae - immunology</subject><subject>Herpesviridae - pathogenicity</subject><subject>Herpesviridae Infections - veterinary</subject><subject>Housing, Animal</subject><subject>Injections</subject><subject>Lesions</subject><subject>Male</subject><subject>Marek Disease - genetics</subject><subject>Marek Disease - immunology</subject><subject>Marek Disease - mortality</subject><subject>Marek Disease - pathology</subject><subject>Marek Disease - prevention & control</subject><subject>Mortality</subject><subject>Poultry Diseases - immunology</subject><subject>Transcriptional regulatory elements</subject><subject>Vaccination</subject><subject>Vaccination - veterinary</subject><subject>Viral diseases</subject><subject>Viral Vaccines - administration & dosage</subject><subject>Virulence</subject><subject>Viruses</subject><issn>0005-2086</issn><issn>1938-4351</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9P3DAQxS1ERReK-AQIH6pyCh3_S5zeECoFiYpKhXPkOJPFsGsvHgep375Bu-qxp5nR-82T3mPsRMCFVNB8FcbaFvQeW4hW2UorI_bZAgBMJcHWH9kh0TOAaNoaDtiBVqpREhbs9bIUjJMrOPCfLuPLOfEhEDpC_oR5g_QW8kTf-K-cCvoSUuQ-xRFznj_mg0p2IRJPI_dPwb_gvL-5_CfEJQ-RLzFiCZ5npEDFRY-f2IfRrQiPd_OIPV5_f7i6qe7uf9xeXd5VXmpdqtrawRptPKhBmVqMjUFwfa2tbUwrlZfO9aMEUzemESM69LbvYbBtqwdvtDpiX7a-m5xeJ6TSrQN5XK1cxDRRZ4U2ta3VDJ5vQZ8TUcax2-SwniN0Arr3crtduTN5urOc-jUO_7hdm7P-eas_U0n5PzZnW2x0qXPLHKh7_C1BKJCyVdpI9RfXKIlp</recordid><startdate>197204</startdate><enddate>197204</enddate><creator>Spencer, J.L</creator><creator>Grunder, A.A</creator><creator>Robertson, A</creator><creator>Speckmann, G.W</creator><general>American Association of Avian Pathologists, Inc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197204</creationdate><title>Attenuated Marek's disease herpesvirus: Protection conferred on strains of chickens varying in genetic resistance</title><author>Spencer, J.L ; Grunder, A.A ; Robertson, A ; Speckmann, G.W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c244t-688d8545c03d3561f75e0ab648875923c2aabf20567571feaec8bb0d8994dc543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Age Factors</topic><topic>animal diseases</topic><topic>animal health</topic><topic>Animals</topic><topic>Antibodies</topic><topic>Antigens, Viral</topic><topic>Avian Leukosis - immunology</topic><topic>Cell culture techniques</topic><topic>Chickens - immunology</topic><topic>Female</topic><topic>Gallid herpesvirus 2</topic><topic>Genetics, Population</topic><topic>Herpesviridae</topic><topic>Herpesviridae - immunology</topic><topic>Herpesviridae - pathogenicity</topic><topic>Herpesviridae Infections - veterinary</topic><topic>Housing, Animal</topic><topic>Injections</topic><topic>Lesions</topic><topic>Male</topic><topic>Marek Disease - genetics</topic><topic>Marek Disease - immunology</topic><topic>Marek Disease - mortality</topic><topic>Marek Disease - pathology</topic><topic>Marek Disease - prevention & control</topic><topic>Mortality</topic><topic>Poultry Diseases - immunology</topic><topic>Transcriptional regulatory elements</topic><topic>Vaccination</topic><topic>Vaccination - veterinary</topic><topic>Viral diseases</topic><topic>Viral Vaccines - administration & dosage</topic><topic>Virulence</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spencer, J.L</creatorcontrib><creatorcontrib>Grunder, A.A</creatorcontrib><creatorcontrib>Robertson, A</creatorcontrib><creatorcontrib>Speckmann, G.W</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Avian diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spencer, J.L</au><au>Grunder, A.A</au><au>Robertson, A</au><au>Speckmann, G.W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Attenuated Marek's disease herpesvirus: Protection conferred on strains of chickens varying in genetic resistance</atitle><jtitle>Avian diseases</jtitle><addtitle>Avian Dis</addtitle><date>1972-04</date><risdate>1972</risdate><volume>16</volume><issue>1</issue><spage>94</spage><epage>107</epage><pages>94-107</pages><issn>0005-2086</issn><eissn>1938-4351</eissn><abstract>Five strains of chickens differing in susceptibility to Marek's disease (MD) were vaccinated with the attenuated BC-1 isolate of MD herpesvirus and were subsequently challenged with virulent virus. Significant protection was conferred to all strains. However, when vaccination was at 1 or 2 days there were significant differences among strains in the incidence of gross lesions of MD. The ranking of strains for susceptibility to MD was not usually altered by vaccination. By comparison, differences in the susceptibility of strains was not observed among chickens vaccinated at 23 days and these were better protected than those vaccinated at 2 days. Vaccination at both 2 and 23 days showed no significant advantage over a single vaccination at 23 days.</abstract><cop>United States</cop><pub>American Association of Avian Pathologists, Inc</pub><pmid>4337320</pmid><doi>10.2307/1588904</doi><tpages>14</tpages></addata></record> |
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| ispartof | Avian diseases, 1972-04, Vol.16 (1), p.94-107 |
| issn | 0005-2086 1938-4351 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing |
| subjects | Age Factors animal diseases animal health Animals Antibodies Antigens, Viral Avian Leukosis - immunology Cell culture techniques Chickens - immunology Female Gallid herpesvirus 2 Genetics, Population Herpesviridae Herpesviridae - immunology Herpesviridae - pathogenicity Herpesviridae Infections - veterinary Housing, Animal Injections Lesions Male Marek Disease - genetics Marek Disease - immunology Marek Disease - mortality Marek Disease - pathology Marek Disease - prevention & control Mortality Poultry Diseases - immunology Transcriptional regulatory elements Vaccination Vaccination - veterinary Viral diseases Viral Vaccines - administration & dosage Virulence Viruses |
| title | Attenuated Marek's disease herpesvirus: Protection conferred on strains of chickens varying in genetic resistance |
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