Extravascular coronary resistance and its relation to microcirculation: Influence of heart rate, end-diastolic pressure and maximal rate of rise of intraventricular pressure

The effect of heart rate, left intraventricular end-diastolic pressure and maximal rate of left intraventricular pressure rise on the extra-vascular resistance to coronary blood flow was evaluated in 19 anesthetized dogs during maximal dilatation of the coronary arteries. The heart was externally st...

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Veröffentlicht in:The American journal of cardiology 1972-05, Vol.29 (5), p.598-603
Hauptverfasser: Raff, Werner Karl, Kosche, Friedrich, Lochner, Wilhelm
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container_title The American journal of cardiology
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creator Raff, Werner Karl
Kosche, Friedrich
Lochner, Wilhelm
description The effect of heart rate, left intraventricular end-diastolic pressure and maximal rate of left intraventricular pressure rise on the extra-vascular resistance to coronary blood flow was evaluated in 19 anesthetized dogs during maximal dilatation of the coronary arteries. The heart was externally stimulated after elimination of the sinus node. It was found that extravascular support increases with increases in heart rate, end-diastolic pressure and maximal rate of rise of left intraventricular pressure.
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adenosine - pharmacology
Animals
Arteries - drug effects
Blood Circulation
Blood Pressure
Coronary Circulation
Coronary Vessels - physiology
Dilatation
Dogs
Electric Stimulation
Heart Rate
Heart Ventricles - drug effects
Hematocrit
Isoproterenol - pharmacology
Microcirculation
Vascular Resistance
title Extravascular coronary resistance and its relation to microcirculation: Influence of heart rate, end-diastolic pressure and maximal rate of rise of intraventricular pressure
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