Targets of Penicillin Action in Escherichia coli
Evidence is presented that the physiological effects of penicillin on E. coli may be due to interaction with at least two specific targets, both of which are enzymes.
Gespeichert in:
| Veröffentlicht in: | Nature (London) 1972-02, Vol.235 (5339), p.426-429 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 429 |
|---|---|
| container_issue | 5339 |
| container_start_page | 426 |
| container_title | Nature (London) |
| container_volume | 235 |
| creator | HARTMANN, RAINER HÖLTJE, JOACHIM-VOLKER SCHWARZ, ULI |
| description | Evidence is presented that the physiological effects of penicillin on
E. coli
may be due to interaction with at least two specific targets, both of which are enzymes. |
| doi_str_mv | 10.1038/235426a0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81428092</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>81428092</sourcerecordid><originalsourceid>FETCH-LOGICAL-c401t-328cf5c6e67a88e2b4701ef43bcfa4c5ef304f6451f48ef42ead7d04346988a83</originalsourceid><addsrcrecordid>eNptkE1LAzEQhoMotVbBP6DsSfSwOvnc9FhK_YCCHup5SdNJm7LdrcnuwX9vZGtPnmaY9-GBeQm5pvBIgesnxqVgysAJGVJRqFwoXZySIQDTOWiuzslFjFsAkLQQAzIQUvKEDAksTFhjG7PGZR9Ye-urytfZxLa-qbO0zaLdYPB2401mm8pfkjNnqohXhzkin8-zxfQ1n7-_vE0n89wKoG3OmbZOWoWqMFojW4oCKDrBl9YZYSU6DsIpIakTOt0ZmlWxAsGFGmttNB-Ru967D81Xh7Etdz5arCpTY9PFUlPBNIxZAu970IYmxoCu3Ae_M-G7pFD-llP-lZPQm4OzW-5wdQQPbaT8oc9jSuo1hnLbdKFOb_7nuu3Z2rRdwKPrCPwAvxd0Uw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81428092</pqid></control><display><type>article</type><title>Targets of Penicillin Action in Escherichia coli</title><source>MEDLINE</source><source>Nature</source><source>SpringerLink Journals - AutoHoldings</source><creator>HARTMANN, RAINER ; HÖLTJE, JOACHIM-VOLKER ; SCHWARZ, ULI</creator><creatorcontrib>HARTMANN, RAINER ; HÖLTJE, JOACHIM-VOLKER ; SCHWARZ, ULI</creatorcontrib><description>Evidence is presented that the physiological effects of penicillin on
E. coli
may be due to interaction with at least two specific targets, both of which are enzymes.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/235426a0</identifier><identifier>PMID: 4553687</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Cell Division - drug effects ; Chromatography, DEAE-Cellulose ; Escherichia coli - drug effects ; Escherichia coli - enzymology ; Glucosidases - antagonists & inhibitors ; Humanities and Social Sciences ; Hydrolases - antagonists & inhibitors ; Hydrolases - isolation & purification ; multidisciplinary ; Penicillins - pharmacology ; Peptidoglycan ; Protease Inhibitors ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1972-02, Vol.235 (5339), p.426-429</ispartof><rights>Springer Nature Limited 1972</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-328cf5c6e67a88e2b4701ef43bcfa4c5ef304f6451f48ef42ead7d04346988a83</citedby><cites>FETCH-LOGICAL-c401t-328cf5c6e67a88e2b4701ef43bcfa4c5ef304f6451f48ef42ead7d04346988a83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/235426a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/235426a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,2725,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4553687$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HARTMANN, RAINER</creatorcontrib><creatorcontrib>HÖLTJE, JOACHIM-VOLKER</creatorcontrib><creatorcontrib>SCHWARZ, ULI</creatorcontrib><title>Targets of Penicillin Action in Escherichia coli</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>Evidence is presented that the physiological effects of penicillin on
E. coli
may be due to interaction with at least two specific targets, both of which are enzymes.</description><subject>Cell Division - drug effects</subject><subject>Chromatography, DEAE-Cellulose</subject><subject>Escherichia coli - drug effects</subject><subject>Escherichia coli - enzymology</subject><subject>Glucosidases - antagonists & inhibitors</subject><subject>Humanities and Social Sciences</subject><subject>Hydrolases - antagonists & inhibitors</subject><subject>Hydrolases - isolation & purification</subject><subject>multidisciplinary</subject><subject>Penicillins - pharmacology</subject><subject>Peptidoglycan</subject><subject>Protease Inhibitors</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1LAzEQhoMotVbBP6DsSfSwOvnc9FhK_YCCHup5SdNJm7LdrcnuwX9vZGtPnmaY9-GBeQm5pvBIgesnxqVgysAJGVJRqFwoXZySIQDTOWiuzslFjFsAkLQQAzIQUvKEDAksTFhjG7PGZR9Ye-urytfZxLa-qbO0zaLdYPB2401mm8pfkjNnqohXhzkin8-zxfQ1n7-_vE0n89wKoG3OmbZOWoWqMFojW4oCKDrBl9YZYSU6DsIpIakTOt0ZmlWxAsGFGmttNB-Ru967D81Xh7Etdz5arCpTY9PFUlPBNIxZAu970IYmxoCu3Ae_M-G7pFD-llP-lZPQm4OzW-5wdQQPbaT8oc9jSuo1hnLbdKFOb_7nuu3Z2rRdwKPrCPwAvxd0Uw</recordid><startdate>19720225</startdate><enddate>19720225</enddate><creator>HARTMANN, RAINER</creator><creator>HÖLTJE, JOACHIM-VOLKER</creator><creator>SCHWARZ, ULI</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19720225</creationdate><title>Targets of Penicillin Action in Escherichia coli</title><author>HARTMANN, RAINER ; HÖLTJE, JOACHIM-VOLKER ; SCHWARZ, ULI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-328cf5c6e67a88e2b4701ef43bcfa4c5ef304f6451f48ef42ead7d04346988a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Cell Division - drug effects</topic><topic>Chromatography, DEAE-Cellulose</topic><topic>Escherichia coli - drug effects</topic><topic>Escherichia coli - enzymology</topic><topic>Glucosidases - antagonists & inhibitors</topic><topic>Humanities and Social Sciences</topic><topic>Hydrolases - antagonists & inhibitors</topic><topic>Hydrolases - isolation & purification</topic><topic>multidisciplinary</topic><topic>Penicillins - pharmacology</topic><topic>Peptidoglycan</topic><topic>Protease Inhibitors</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HARTMANN, RAINER</creatorcontrib><creatorcontrib>HÖLTJE, JOACHIM-VOLKER</creatorcontrib><creatorcontrib>SCHWARZ, ULI</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HARTMANN, RAINER</au><au>HÖLTJE, JOACHIM-VOLKER</au><au>SCHWARZ, ULI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Targets of Penicillin Action in Escherichia coli</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1972-02-25</date><risdate>1972</risdate><volume>235</volume><issue>5339</issue><spage>426</spage><epage>429</epage><pages>426-429</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>Evidence is presented that the physiological effects of penicillin on
E. coli
may be due to interaction with at least two specific targets, both of which are enzymes.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>4553687</pmid><doi>10.1038/235426a0</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1972-02, Vol.235 (5339), p.426-429 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81428092 |
| source | MEDLINE; Nature; SpringerLink Journals - AutoHoldings |
| subjects | Cell Division - drug effects Chromatography, DEAE-Cellulose Escherichia coli - drug effects Escherichia coli - enzymology Glucosidases - antagonists & inhibitors Humanities and Social Sciences Hydrolases - antagonists & inhibitors Hydrolases - isolation & purification multidisciplinary Penicillins - pharmacology Peptidoglycan Protease Inhibitors Science Science (multidisciplinary) |
| title | Targets of Penicillin Action in Escherichia coli |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T21%3A11%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Targets%20of%20Penicillin%20Action%20in%20Escherichia%20coli&rft.jtitle=Nature%20(London)&rft.au=HARTMANN,%20RAINER&rft.date=1972-02-25&rft.volume=235&rft.issue=5339&rft.spage=426&rft.epage=429&rft.pages=426-429&rft.issn=0028-0836&rft.eissn=1476-4687&rft_id=info:doi/10.1038/235426a0&rft_dat=%3Cproquest_cross%3E81428092%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81428092&rft_id=info:pmid/4553687&rfr_iscdi=true |