Value of serum copper measurement in lymphomas and several other malignancies
Of 42 patients with lymphomas (Hodgkin's disease, reticulum cell sarcoma and lymphosarcoma) 30 (69%) had raised serum copper concentrations. Twenty‐three of 24 who had generalized disease had increased serum copper level and, of the 18 with localized disease, 12 had normal, six had raised serum...
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Veröffentlicht in: | Cancer 1972-05, Vol.29 (5), p.1193-1198 |
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creator | Mortazavi, S. H. Bani‐Hashemi, A. Mozafari, M. Raffi, A. |
description | Of 42 patients with lymphomas (Hodgkin's disease, reticulum cell sarcoma and lymphosarcoma) 30 (69%) had raised serum copper concentrations. Twenty‐three of 24 who had generalized disease had increased serum copper level and, of the 18 with localized disease, 12 had normal, six had raised serum copper. In all, the clinical result of the treatment given to the patient correlated with the alteration in serum copper. The findings were the same for Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma. Serum copper was found to be greatly elevated also in multiple myeloma, and lymphoepithelial tumors (Schminke tumor). These observations suggest that serum copper measurements can be used as prognostic and theraputic index, and that this is a useful auxiliary test in the management of patients with lymphomas. |
doi_str_mv | 10.1002/1097-0142(197205)29:5<1193::AID-CNCR2820290510>3.0.CO;2-6 |
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H. ; Bani‐Hashemi, A. ; Mozafari, M. ; Raffi, A.</creator><creatorcontrib>Mortazavi, S. H. ; Bani‐Hashemi, A. ; Mozafari, M. ; Raffi, A.</creatorcontrib><description>Of 42 patients with lymphomas (Hodgkin's disease, reticulum cell sarcoma and lymphosarcoma) 30 (69%) had raised serum copper concentrations. Twenty‐three of 24 who had generalized disease had increased serum copper level and, of the 18 with localized disease, 12 had normal, six had raised serum copper. In all, the clinical result of the treatment given to the patient correlated with the alteration in serum copper. The findings were the same for Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma. Serum copper was found to be greatly elevated also in multiple myeloma, and lymphoepithelial tumors (Schminke tumor). These observations suggest that serum copper measurements can be used as prognostic and theraputic index, and that this is a useful auxiliary test in the management of patients with lymphomas.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(197205)29:5<1193::AID-CNCR2820290510>3.0.CO;2-6</identifier><identifier>PMID: 4553758</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Carcinoma, Squamous Cell - diagnosis ; Clinical Trials as Topic ; Copper - blood ; Hodgkin Disease - diagnosis ; Humans ; Lymphoma - blood ; Lymphoma - diagnosis ; Lymphoma, Large B-Cell, Diffuse - diagnosis ; Lymphoma, Non-Hodgkin - diagnosis ; Methods ; Multiple Myeloma - diagnosis ; Plasmacytoma - diagnosis ; Prognosis</subject><ispartof>Cancer, 1972-05, Vol.29 (5), p.1193-1198</ispartof><rights>Copyright © 1972 American Cancer Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4630-fb1c2fc083118ebb93d0cffa907f8811fe6866e6ffd6ba20843f9d4fcdddddf03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27933,27934</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4553758$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mortazavi, S. H.</creatorcontrib><creatorcontrib>Bani‐Hashemi, A.</creatorcontrib><creatorcontrib>Mozafari, M.</creatorcontrib><creatorcontrib>Raffi, A.</creatorcontrib><title>Value of serum copper measurement in lymphomas and several other malignancies</title><title>Cancer</title><addtitle>Cancer</addtitle><description>Of 42 patients with lymphomas (Hodgkin's disease, reticulum cell sarcoma and lymphosarcoma) 30 (69%) had raised serum copper concentrations. Twenty‐three of 24 who had generalized disease had increased serum copper level and, of the 18 with localized disease, 12 had normal, six had raised serum copper. In all, the clinical result of the treatment given to the patient correlated with the alteration in serum copper. The findings were the same for Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma. Serum copper was found to be greatly elevated also in multiple myeloma, and lymphoepithelial tumors (Schminke tumor). These observations suggest that serum copper measurements can be used as prognostic and theraputic index, and that this is a useful auxiliary test in the management of patients with lymphomas.</description><subject>Carcinoma, Squamous Cell - diagnosis</subject><subject>Clinical Trials as Topic</subject><subject>Copper - blood</subject><subject>Hodgkin Disease - diagnosis</subject><subject>Humans</subject><subject>Lymphoma - blood</subject><subject>Lymphoma - diagnosis</subject><subject>Lymphoma, Large B-Cell, Diffuse - diagnosis</subject><subject>Lymphoma, Non-Hodgkin - diagnosis</subject><subject>Methods</subject><subject>Multiple Myeloma - diagnosis</subject><subject>Plasmacytoma - diagnosis</subject><subject>Prognosis</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF-L1DAUxYMo67j6EYQ-iT50vEmaNBlFGOqqC6sDoqJPlzS9cSv9ZzN1mW9vywwL-iB4X8LlnJyT_BjbclhzAPGcg81T4Jl4ym0uQD0TdqNecm7lZrO9fJ0WH4qPwggQFhSHV3IN62L3QqT6Dlvd3r3LVgBgUpXJr_fZgxh_zGsulDxjZ5lSMldmxd5_cc1ESR-SSOPUJr4fBhqTllycRmqp2yd1lzSHdrjuWxcT11Wz8xeNrkn6_fVidU39vXOdryk-ZPeCayI9Op3n7PObi0_Fu_Rq9_ay2F6lPtMS0lByL4IHIzk3VJZWVuBDcBbyYAzngbTRmnQIlS6dAJPJYKss-GqZAPKcPTnmDmP_c6K4x7aOnprGddRPEc38_UxDPhu_HY1-7GMcKeAw1q0bD8gBF9S44MIFFx5Ro7CocEGNOKPGP1GjRMBihwL1nP349IipbKm6TT6xnfXqqN_UDR3-p_ifvX8p8jcIl5yo</recordid><startdate>197205</startdate><enddate>197205</enddate><creator>Mortazavi, S. H.</creator><creator>Bani‐Hashemi, A.</creator><creator>Mozafari, M.</creator><creator>Raffi, A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197205</creationdate><title>Value of serum copper measurement in lymphomas and several other malignancies</title><author>Mortazavi, S. H. ; Bani‐Hashemi, A. ; Mozafari, M. ; Raffi, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4630-fb1c2fc083118ebb93d0cffa907f8811fe6866e6ffd6ba20843f9d4fcdddddf03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Carcinoma, Squamous Cell - diagnosis</topic><topic>Clinical Trials as Topic</topic><topic>Copper - blood</topic><topic>Hodgkin Disease - diagnosis</topic><topic>Humans</topic><topic>Lymphoma - blood</topic><topic>Lymphoma - diagnosis</topic><topic>Lymphoma, Large B-Cell, Diffuse - diagnosis</topic><topic>Lymphoma, Non-Hodgkin - diagnosis</topic><topic>Methods</topic><topic>Multiple Myeloma - diagnosis</topic><topic>Plasmacytoma - diagnosis</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mortazavi, S. H.</creatorcontrib><creatorcontrib>Bani‐Hashemi, A.</creatorcontrib><creatorcontrib>Mozafari, M.</creatorcontrib><creatorcontrib>Raffi, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mortazavi, S. H.</au><au>Bani‐Hashemi, A.</au><au>Mozafari, M.</au><au>Raffi, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of serum copper measurement in lymphomas and several other malignancies</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1972-05</date><risdate>1972</risdate><volume>29</volume><issue>5</issue><spage>1193</spage><epage>1198</epage><pages>1193-1198</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Of 42 patients with lymphomas (Hodgkin's disease, reticulum cell sarcoma and lymphosarcoma) 30 (69%) had raised serum copper concentrations. Twenty‐three of 24 who had generalized disease had increased serum copper level and, of the 18 with localized disease, 12 had normal, six had raised serum copper. In all, the clinical result of the treatment given to the patient correlated with the alteration in serum copper. The findings were the same for Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma. Serum copper was found to be greatly elevated also in multiple myeloma, and lymphoepithelial tumors (Schminke tumor). These observations suggest that serum copper measurements can be used as prognostic and theraputic index, and that this is a useful auxiliary test in the management of patients with lymphomas.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>4553758</pmid><doi>10.1002/1097-0142(197205)29:5<1193::AID-CNCR2820290510>3.0.CO;2-6</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Carcinoma, Squamous Cell - diagnosis Clinical Trials as Topic Copper - blood Hodgkin Disease - diagnosis Humans Lymphoma - blood Lymphoma - diagnosis Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Non-Hodgkin - diagnosis Methods Multiple Myeloma - diagnosis Plasmacytoma - diagnosis Prognosis |
title | Value of serum copper measurement in lymphomas and several other malignancies |
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