Intramuscularly and orally administered lidocaine in the treatment of ventricular arrhythmias in acute myocardial infarction

An intramuscular injection of 2.5 ml of 10 percent lidocaine was given to 26 cardiac patients. An effective mean plasma level (1 mg/liter or more) was reached in 5 minutes and persisted for 120 minutes; the highest mean level (2.2 mg/liter, SEM ± 0.18) was reached after 30 minutes. In 15 patients wh...

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