Spin Echo Studies on Cellular Water
HIGH resolution nuclear magnetic resonance (NMR) studies on rat skeletal muscle have recently shown that cellular water produces an absorption line almost ten times as broad as the line width of pure water 1 . This suggests that these water molecules are at least partly bounded such that the proton...
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| Veröffentlicht in: | Nature (London) 1972-01, Vol.235 (5334), p.170-171 |
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| container_issue | 5334 |
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| container_title | Nature (London) |
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| creator | CHANG, D. C HAZLEWOOD, C. F NICHOLS, B. L RORSCHACH, H. E |
| description | HIGH resolution nuclear magnetic resonance (NMR) studies on rat skeletal muscle have recently shown that cellular water produces an absorption line almost ten times as broad as the line width of pure water
1
. This suggests that these water molecules are at least partly bounded such that the proton correlation time is increased. Similar observations have also been made for deuterated water in skeletal muscle
2
and for H
2
O in other tissues
3–5
. Our results further substantiate the notion that ordered water exists in biological tissue and rules out several criticisms of this interpretation. |
| doi_str_mv | 10.1038/235170a0 |
| format | Article |
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1
. This suggests that these water molecules are at least partly bounded such that the proton correlation time is increased. Similar observations have also been made for deuterated water in skeletal muscle
2
and for H
2
O in other tissues
3–5
. Our results further substantiate the notion that ordered water exists in biological tissue and rules out several criticisms of this interpretation.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/235170a0</identifier><identifier>PMID: 4551228</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Body Fluids - analysis ; Body Water - analysis ; Diffusion ; Glass ; Humanities and Social Sciences ; letter ; Magnetic Resonance Spectroscopy ; multidisciplinary ; Muscles - analysis ; Rats ; Science ; Science (multidisciplinary) ; Water - analysis</subject><ispartof>Nature (London), 1972-01, Vol.235 (5334), p.170-171</ispartof><rights>Springer Nature Limited 1972</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-c1d3adc3cf19e3493791244109a9bd2d183207f9f3f8b06691e5d5a588cc75ea3</citedby><cites>FETCH-LOGICAL-c335t-c1d3adc3cf19e3493791244109a9bd2d183207f9f3f8b06691e5d5a588cc75ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/235170a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/235170a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,2726,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4551228$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CHANG, D. C</creatorcontrib><creatorcontrib>HAZLEWOOD, C. F</creatorcontrib><creatorcontrib>NICHOLS, B. L</creatorcontrib><creatorcontrib>RORSCHACH, H. E</creatorcontrib><title>Spin Echo Studies on Cellular Water</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>HIGH resolution nuclear magnetic resonance (NMR) studies on rat skeletal muscle have recently shown that cellular water produces an absorption line almost ten times as broad as the line width of pure water
1
. This suggests that these water molecules are at least partly bounded such that the proton correlation time is increased. Similar observations have also been made for deuterated water in skeletal muscle
2
and for H
2
O in other tissues
3–5
. Our results further substantiate the notion that ordered water exists in biological tissue and rules out several criticisms of this interpretation.</description><subject>Animals</subject><subject>Body Fluids - analysis</subject><subject>Body Water - analysis</subject><subject>Diffusion</subject><subject>Glass</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>multidisciplinary</subject><subject>Muscles - analysis</subject><subject>Rats</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Water - analysis</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtLAzEUhYMotVbBP6AMCKKL0ZvXTLIspT6g4KKKy5AmGZ0ynanJZOG_NzK1K1d3cT4-zj0InWO4w0DFPaEcl6DhAI0xK4ucFaI8RGMAInIQtDhGJyGsASBhbIRGjHNMiBijq-W2brO5-eyyZR9t7ULWtdnMNU1stM_ede_8KTqqdBPc2e5O0NvD_HX2lC9eHp9n00VuKOV9brCl2hpqKiwdZZKWEhPGMEgtV5ZYLCiBspIVrcQKikJixy3XXAhjSu40naDrwbv13Vd0oVebOphURbeui0EJTEXqzxN4M4DGdyF4V6mtrzfafysM6ncP9bdHQi92zrjaOLsHdwOk_HbIQ0raD-fVuou-TW_-57oc2Fb30bu9aw_8AAbubsU</recordid><startdate>19720121</startdate><enddate>19720121</enddate><creator>CHANG, D. C</creator><creator>HAZLEWOOD, C. F</creator><creator>NICHOLS, B. L</creator><creator>RORSCHACH, H. E</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19720121</creationdate><title>Spin Echo Studies on Cellular Water</title><author>CHANG, D. C ; HAZLEWOOD, C. F ; NICHOLS, B. L ; RORSCHACH, H. E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-c1d3adc3cf19e3493791244109a9bd2d183207f9f3f8b06691e5d5a588cc75ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Animals</topic><topic>Body Fluids - analysis</topic><topic>Body Water - analysis</topic><topic>Diffusion</topic><topic>Glass</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>multidisciplinary</topic><topic>Muscles - analysis</topic><topic>Rats</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Water - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CHANG, D. C</creatorcontrib><creatorcontrib>HAZLEWOOD, C. F</creatorcontrib><creatorcontrib>NICHOLS, B. L</creatorcontrib><creatorcontrib>RORSCHACH, H. E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CHANG, D. C</au><au>HAZLEWOOD, C. F</au><au>NICHOLS, B. L</au><au>RORSCHACH, H. E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spin Echo Studies on Cellular Water</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1972-01-21</date><risdate>1972</risdate><volume>235</volume><issue>5334</issue><spage>170</spage><epage>171</epage><pages>170-171</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>HIGH resolution nuclear magnetic resonance (NMR) studies on rat skeletal muscle have recently shown that cellular water produces an absorption line almost ten times as broad as the line width of pure water
1
. This suggests that these water molecules are at least partly bounded such that the proton correlation time is increased. Similar observations have also been made for deuterated water in skeletal muscle
2
and for H
2
O in other tissues
3–5
. Our results further substantiate the notion that ordered water exists in biological tissue and rules out several criticisms of this interpretation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>4551228</pmid><doi>10.1038/235170a0</doi><tpages>2</tpages></addata></record> |
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| ispartof | Nature (London), 1972-01, Vol.235 (5334), p.170-171 |
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| language | eng |
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| source | MEDLINE; Nature; SpringerLink Journals - AutoHoldings |
| subjects | Animals Body Fluids - analysis Body Water - analysis Diffusion Glass Humanities and Social Sciences letter Magnetic Resonance Spectroscopy multidisciplinary Muscles - analysis Rats Science Science (multidisciplinary) Water - analysis |
| title | Spin Echo Studies on Cellular Water |
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