The Development of Resistance in Mice Immunized with Soluble Antigen Derived from Bacterium Tularense

The Development of Resistance in Mice Immunized with Soluble Antigen Derived from Bacterium Tularense

White mice immunized with soluble antigens obtained from B. tularense showed specific resistance to challenge within 24 hours after immunization and developed circulating, protective antibodies within 72 hours. Mice so immunized failed to develop detectable agglutinins.

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Bibliographische Detailangaben
Veröffentlicht in:The Journal of immunology (1950) 1954-10, Vol.73 (4), p.221-225
Hauptverfasser: Larson, Carl L, Bell, J. Frederick, Owen, Cora R
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies
Antigens
Francisella tularensis
Immunization
Mice
Old Medline
Tularemia - immunology
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Beschreibung
Zusammenfassung:White mice immunized with soluble antigens obtained from B. tularense showed specific resistance to challenge within 24 hours after immunization and developed circulating, protective antibodies within 72 hours. Mice so immunized failed to develop detectable agglutinins.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.73.4.221