Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma
The observations collected from hematologic examinations of 100 patients with metastatic carcinoma are reported. Histologic evaluation of the marrow needle biopsy and aspirate revealed the biopsy showing clearcut evidence of tumor in 94 patients, while the aspirate was positive in only 43. The other...
Gespeichert in:
| Veröffentlicht in: | Cancer 1972-03, Vol.29 (3), p.778-783 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 783 |
|---|---|
| container_issue | 3 |
| container_start_page | 778 |
| container_title | Cancer |
| container_volume | 29 |
| creator | Contreras, Elvia Ellis, Lawrence D. Lee, Robert E. |
| description | The observations collected from hematologic examinations of 100 patients with metastatic carcinoma are reported. Histologic evaluation of the marrow needle biopsy and aspirate revealed the biopsy showing clearcut evidence of tumor in 94 patients, while the aspirate was positive in only 43. The other common morphological alterations included fibrosis (87%) and myelosclerosis (67%). Mild anemia was noted in 74 patients of this group and thrombocytopenia in 25 patients out of the 66 whose platelet counts were recorded. Leukoerythroblastosis was noted in only 19 patients out of the 79 patients whose peripheral blood smears were available for examination. The results point to the superiority of the bone marrow biopsy over the aspirate in the diagnosis of metastatic carcinoma. Rather than leukoerythroblastosis which occurred in only 19 of this group, we found mild anemia and thrombocytopenia to be more common. |
| doi_str_mv | 10.1002/1097-0142(197203)29:3<778::AID-CNCR2820290334>3.0.CO;2-# |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81381884</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>81381884</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3754-c0b9f9177c9cd4a8e5af452b446f5967f4cc46209d11a219d1e0184e06496b783</originalsourceid><addsrcrecordid>eNqVkF1r2zAUhsVYSdOPn1AwDEZ74fTow5aUlrHitU2hNFDW0DshK_KmYVup5RDy76c0IbBdDHZ1OHpfveecB6GvGEYYgFxikDwFzMg5lpwAvSByTK85F-PxzcO3tHgqnokgQCRQyr7QEYyK6RVJP31Aw_3Xj2gIACLNGH09REch_IotJxkdoEEGOeQZG6LJTNdLm_gq6X_apPStTRrddX6VlM4vwjpx7bsyd_pH64MLG2tjex163TuTGN0Z1_pGn6CDStfBnu7qMXq5u_1eTNLH6f1DcfOYGsozlhooZSUx50aaOdPCZrpiGSkZy6tM5rxixrCcgJxjrAmOxQIWzELOZF5yQY_R523uovNvSxt61bhgbF3r1vplUAJTgYVg0TjbGk3nQ-hspRadi7etFQa1gaw2pNSGlNpCVkQqqiJkpSJk9SfkqIAqporE4LPdBsuysfN97I5p1PVWX7narv9j6j-G_vVOfwP2GZZZ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81381884</pqid></control><display><type>article</type><title>Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Contreras, Elvia ; Ellis, Lawrence D. ; Lee, Robert E.</creator><creatorcontrib>Contreras, Elvia ; Ellis, Lawrence D. ; Lee, Robert E.</creatorcontrib><description>The observations collected from hematologic examinations of 100 patients with metastatic carcinoma are reported. Histologic evaluation of the marrow needle biopsy and aspirate revealed the biopsy showing clearcut evidence of tumor in 94 patients, while the aspirate was positive in only 43. The other common morphological alterations included fibrosis (87%) and myelosclerosis (67%). Mild anemia was noted in 74 patients of this group and thrombocytopenia in 25 patients out of the 66 whose platelet counts were recorded. Leukoerythroblastosis was noted in only 19 patients out of the 79 patients whose peripheral blood smears were available for examination. The results point to the superiority of the bone marrow biopsy over the aspirate in the diagnosis of metastatic carcinoma. Rather than leukoerythroblastosis which occurred in only 19 of this group, we found mild anemia and thrombocytopenia to be more common.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(197203)29:3<778::AID-CNCR2820290334>3.0.CO;2-#</identifier><identifier>PMID: 5060654</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Aged ; Anemia - epidemiology ; Anemia, Myelophthisic - epidemiology ; Biopsy ; Bone Marrow - pathology ; Breast Neoplasms - pathology ; Colonic Neoplasms - pathology ; Female ; Humans ; Male ; Methods ; Middle Aged ; Neoplasm Metastasis - diagnosis ; Primary Myelofibrosis - pathology ; Prostatic Neoplasms - pathology ; Thrombocytopenia - epidemiology</subject><ispartof>Cancer, 1972-03, Vol.29 (3), p.778-783</ispartof><rights>Copyright © 1972 American Cancer Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3754-c0b9f9177c9cd4a8e5af452b446f5967f4cc46209d11a219d1e0184e06496b783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5060654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Contreras, Elvia</creatorcontrib><creatorcontrib>Ellis, Lawrence D.</creatorcontrib><creatorcontrib>Lee, Robert E.</creatorcontrib><title>Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma</title><title>Cancer</title><addtitle>Cancer</addtitle><description>The observations collected from hematologic examinations of 100 patients with metastatic carcinoma are reported. Histologic evaluation of the marrow needle biopsy and aspirate revealed the biopsy showing clearcut evidence of tumor in 94 patients, while the aspirate was positive in only 43. The other common morphological alterations included fibrosis (87%) and myelosclerosis (67%). Mild anemia was noted in 74 patients of this group and thrombocytopenia in 25 patients out of the 66 whose platelet counts were recorded. Leukoerythroblastosis was noted in only 19 patients out of the 79 patients whose peripheral blood smears were available for examination. The results point to the superiority of the bone marrow biopsy over the aspirate in the diagnosis of metastatic carcinoma. Rather than leukoerythroblastosis which occurred in only 19 of this group, we found mild anemia and thrombocytopenia to be more common.</description><subject>Adult</subject><subject>Aged</subject><subject>Anemia - epidemiology</subject><subject>Anemia, Myelophthisic - epidemiology</subject><subject>Biopsy</subject><subject>Bone Marrow - pathology</subject><subject>Breast Neoplasms - pathology</subject><subject>Colonic Neoplasms - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis - diagnosis</subject><subject>Primary Myelofibrosis - pathology</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Thrombocytopenia - epidemiology</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF1r2zAUhsVYSdOPn1AwDEZ74fTow5aUlrHitU2hNFDW0DshK_KmYVup5RDy76c0IbBdDHZ1OHpfveecB6GvGEYYgFxikDwFzMg5lpwAvSByTK85F-PxzcO3tHgqnokgQCRQyr7QEYyK6RVJP31Aw_3Xj2gIACLNGH09REch_IotJxkdoEEGOeQZG6LJTNdLm_gq6X_apPStTRrddX6VlM4vwjpx7bsyd_pH64MLG2tjex163TuTGN0Z1_pGn6CDStfBnu7qMXq5u_1eTNLH6f1DcfOYGsozlhooZSUx50aaOdPCZrpiGSkZy6tM5rxixrCcgJxjrAmOxQIWzELOZF5yQY_R523uovNvSxt61bhgbF3r1vplUAJTgYVg0TjbGk3nQ-hspRadi7etFQa1gaw2pNSGlNpCVkQqqiJkpSJk9SfkqIAqporE4LPdBsuysfN97I5p1PVWX7narv9j6j-G_vVOfwP2GZZZ</recordid><startdate>197203</startdate><enddate>197203</enddate><creator>Contreras, Elvia</creator><creator>Ellis, Lawrence D.</creator><creator>Lee, Robert E.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197203</creationdate><title>Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma</title><author>Contreras, Elvia ; Ellis, Lawrence D. ; Lee, Robert E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3754-c0b9f9177c9cd4a8e5af452b446f5967f4cc46209d11a219d1e0184e06496b783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anemia - epidemiology</topic><topic>Anemia, Myelophthisic - epidemiology</topic><topic>Biopsy</topic><topic>Bone Marrow - pathology</topic><topic>Breast Neoplasms - pathology</topic><topic>Colonic Neoplasms - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis - diagnosis</topic><topic>Primary Myelofibrosis - pathology</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Thrombocytopenia - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Contreras, Elvia</creatorcontrib><creatorcontrib>Ellis, Lawrence D.</creatorcontrib><creatorcontrib>Lee, Robert E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Contreras, Elvia</au><au>Ellis, Lawrence D.</au><au>Lee, Robert E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1972-03</date><risdate>1972</risdate><volume>29</volume><issue>3</issue><spage>778</spage><epage>783</epage><pages>778-783</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>The observations collected from hematologic examinations of 100 patients with metastatic carcinoma are reported. Histologic evaluation of the marrow needle biopsy and aspirate revealed the biopsy showing clearcut evidence of tumor in 94 patients, while the aspirate was positive in only 43. The other common morphological alterations included fibrosis (87%) and myelosclerosis (67%). Mild anemia was noted in 74 patients of this group and thrombocytopenia in 25 patients out of the 66 whose platelet counts were recorded. Leukoerythroblastosis was noted in only 19 patients out of the 79 patients whose peripheral blood smears were available for examination. The results point to the superiority of the bone marrow biopsy over the aspirate in the diagnosis of metastatic carcinoma. Rather than leukoerythroblastosis which occurred in only 19 of this group, we found mild anemia and thrombocytopenia to be more common.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>5060654</pmid><doi>10.1002/1097-0142(197203)29:3<778::AID-CNCR2820290334>3.0.CO;2-#</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0008-543X |
| ispartof | Cancer, 1972-03, Vol.29 (3), p.778-783 |
| issn | 0008-543X 1097-0142 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81381884 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Aged Anemia - epidemiology Anemia, Myelophthisic - epidemiology Biopsy Bone Marrow - pathology Breast Neoplasms - pathology Colonic Neoplasms - pathology Female Humans Male Methods Middle Aged Neoplasm Metastasis - diagnosis Primary Myelofibrosis - pathology Prostatic Neoplasms - pathology Thrombocytopenia - epidemiology |
| title | Value of the bone marrow biopsy in the diagnosis of metastatic carcinoma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T09%3A26%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Value%20of%20the%20bone%20marrow%20biopsy%20in%20the%20diagnosis%20of%20metastatic%20carcinoma&rft.jtitle=Cancer&rft.au=Contreras,%20Elvia&rft.date=1972-03&rft.volume=29&rft.issue=3&rft.spage=778&rft.epage=783&rft.pages=778-783&rft.issn=0008-543X&rft.eissn=1097-0142&rft_id=info:doi/10.1002/1097-0142(197203)29:3%3C778::AID-CNCR2820290334%3E3.0.CO;2-%23&rft_dat=%3Cproquest_cross%3E81381884%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81381884&rft_id=info:pmid/5060654&rfr_iscdi=true |