Enhanced stimulant properties of (+)-amphetamine after chronic reserpine treatment in the rat: mediation by hypophagia and weight loss

Rats were treated with daily i.p. injections of reserpine (0.5 mg/kg) or saline for 10 days. Twenty-four hours after the last injection they were given (+)-amphetamine (0.25, 0.50, or 1 mg/kg) or saline and their locomotor activity was measured for 3 hr. In accordance with previous reports, (+)-amph...

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Veröffentlicht in:	Neuropharmacology 1972, Vol.11 (1), p.57-67
Hauptverfasser:	Fibiger, H.C., Trimbach, C., Campbell, B.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Appetite Depressants - pharmacology Body Weight - drug effects Dextroamphetamine - administration & dosage Dextroamphetamine - pharmacology Feeding Behavior - drug effects Male Motor Activity - drug effects Rats Reserpine - administration & dosage Reserpine - pharmacology Stimulation, Chemical
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