Hormonal regulation of the immune response: II. Influence of pituitary and adrenal activity on immune responsiveness in vitro

Exposure of mice to acceleration stress, ether anesthesia or injection of adrenocorticotropic hormone (ACTH) resulted in a transitory increase of plasma corticosterone concentrations. Spleen cells explanted at the moment of increased levels of corticosteroids reacted poorly to antigen in vitro. Adre...

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