Hyperbaric bupivacaine for spinal anesthesia in cesarean section
The efficacy and safety of 0.5% hyperbaric bupivacaine (Sensorcaine, Astra) was evaluated in 22 patients undergoing elective cesarean section under spinal anesthesia. The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. P...
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| Veröffentlicht in: | Anesthesia and analgesia 1984-11, Vol.63 (11), p.1009-1013 |
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| container_title | Anesthesia and analgesia |
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| creator | SANTOS, A PEDERSEN, H FINSTER, M EDSTRÖM, H |
| description | The efficacy and safety of 0.5% hyperbaric bupivacaine (Sensorcaine, Astra) was evaluated in 22 patients undergoing elective cesarean section under spinal anesthesia. The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. Patients were placed in head-down tilt immediately after subarachnoid injection. The mean spread of analgesia was to T3, which was reached in 10-15 min. Regression was complete in 258 +/- 16 min. Complete motor paralysis of lower extremities occurred in only two patients. Complete recovery of motor function in all patients was evident in less than 2.5 h. All infants were vigorous at birth and there were no serious maternal complications. The incidence of hypotension was 4.5%, the lowest reported as a consequence of spinal anesthesia in this group of patients. A technique involving the use of reduced doses of hyperbaric bupivacaine (0.5%) in conjunction with head-down tilt appears to be useful for spinal anesthesia for cesarean section. |
| doi_str_mv | 10.1213/00000539-198411000-00009 |
| format | Article |
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The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. Patients were placed in head-down tilt immediately after subarachnoid injection. The mean spread of analgesia was to T3, which was reached in 10-15 min. Regression was complete in 258 +/- 16 min. Complete motor paralysis of lower extremities occurred in only two patients. Complete recovery of motor function in all patients was evident in less than 2.5 h. All infants were vigorous at birth and there were no serious maternal complications. The incidence of hypotension was 4.5%, the lowest reported as a consequence of spinal anesthesia in this group of patients. A technique involving the use of reduced doses of hyperbaric bupivacaine (0.5%) in conjunction with head-down tilt appears to be useful for spinal anesthesia for cesarean section.</description><identifier>ISSN: 0003-2999</identifier><identifier>EISSN: 1526-7598</identifier><identifier>DOI: 10.1213/00000539-198411000-00009</identifier><identifier>PMID: 6496970</identifier><identifier>CODEN: AACRAT</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Abdominal surgery. Urology. Gynecology. Obstetrics ; Adult ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia, Obstetrical ; Anesthesia, Spinal ; Anesthesia. Intensive care medicine. Transfusions. 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The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. Patients were placed in head-down tilt immediately after subarachnoid injection. The mean spread of analgesia was to T3, which was reached in 10-15 min. Regression was complete in 258 +/- 16 min. Complete motor paralysis of lower extremities occurred in only two patients. Complete recovery of motor function in all patients was evident in less than 2.5 h. All infants were vigorous at birth and there were no serious maternal complications. The incidence of hypotension was 4.5%, the lowest reported as a consequence of spinal anesthesia in this group of patients. A technique involving the use of reduced doses of hyperbaric bupivacaine (0.5%) in conjunction with head-down tilt appears to be useful for spinal anesthesia for cesarean section.</description><subject>Abdominal surgery. Urology. Gynecology. Obstetrics</subject><subject>Adult</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia, Obstetrical</subject><subject>Anesthesia, Spinal</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure - drug effects</subject><subject>Bupivacaine - administration & dosage</subject><subject>Cesarean Section</subject><subject>Female</subject><subject>Heart Rate - drug effects</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Posture</subject><subject>Pregnancy</subject><issn>0003-2999</issn><issn>1526-7598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UMFOwzAMjRBojMEnIOWAuBWSpknjG2gChjSJC5wrJ01FUNeWZEXa35OyMV-s9_yebT1CKGd3POfink0lBWQcdMF5AtnEwAmZc5mrrJSgT8k8USLLAeCcXMT4lSBnWs3ITBWgoGRz8rDaDS4YDN5SMw7-By36ztGmDzQOvsOWYufi9tNFj9R31LqIwWFHo7Nb33eX5KzBNrqrQ1-Qj-en9-UqW7-9vC4f15kVGraZsDnnqhBONtaWpmaoauM02NrqMrdGlABMgZROGgSGICwTkpUwEQU3YkFu93uH0H-P6aNq46N1bZve68dYaS5yyAuehHovtKGPMbimGoLfYNhVnFVTeNV_eNUxvD8KkvX6cGM0G1cfjYe00vzmMMdosW0CdtbHo0wDY0op8QvDfXZ4</recordid><startdate>198411</startdate><enddate>198411</enddate><creator>SANTOS, A</creator><creator>PEDERSEN, H</creator><creator>FINSTER, M</creator><creator>EDSTRÖM, H</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198411</creationdate><title>Hyperbaric bupivacaine for spinal anesthesia in cesarean section</title><author>SANTOS, A ; PEDERSEN, H ; FINSTER, M ; EDSTRÖM, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-3c211643e5fcc7bd0a6dbe89cdc872cb379906955e5ba90a93c0350795e5b41b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Abdominal surgery. Urology. Gynecology. Obstetrics</topic><topic>Adult</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia, Obstetrical</topic><topic>Anesthesia, Spinal</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - drug effects</topic><topic>Bupivacaine - administration & dosage</topic><topic>Cesarean Section</topic><topic>Female</topic><topic>Heart Rate - drug effects</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Posture</topic><topic>Pregnancy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SANTOS, A</creatorcontrib><creatorcontrib>PEDERSEN, H</creatorcontrib><creatorcontrib>FINSTER, M</creatorcontrib><creatorcontrib>EDSTRÖM, H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesia and analgesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SANTOS, A</au><au>PEDERSEN, H</au><au>FINSTER, M</au><au>EDSTRÖM, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hyperbaric bupivacaine for spinal anesthesia in cesarean section</atitle><jtitle>Anesthesia and analgesia</jtitle><addtitle>Anesth Analg</addtitle><date>1984-11</date><risdate>1984</risdate><volume>63</volume><issue>11</issue><spage>1009</spage><epage>1013</epage><pages>1009-1013</pages><issn>0003-2999</issn><eissn>1526-7598</eissn><coden>AACRAT</coden><abstract>The efficacy and safety of 0.5% hyperbaric bupivacaine (Sensorcaine, Astra) was evaluated in 22 patients undergoing elective cesarean section under spinal anesthesia. The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. Patients were placed in head-down tilt immediately after subarachnoid injection. The mean spread of analgesia was to T3, which was reached in 10-15 min. Regression was complete in 258 +/- 16 min. Complete motor paralysis of lower extremities occurred in only two patients. Complete recovery of motor function in all patients was evident in less than 2.5 h. All infants were vigorous at birth and there were no serious maternal complications. The incidence of hypotension was 4.5%, the lowest reported as a consequence of spinal anesthesia in this group of patients. A technique involving the use of reduced doses of hyperbaric bupivacaine (0.5%) in conjunction with head-down tilt appears to be useful for spinal anesthesia for cesarean section.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>6496970</pmid><doi>10.1213/00000539-198411000-00009</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Anesthesia and analgesia, 1984-11, Vol.63 (11), p.1009-1013 |
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| language | eng |
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| source | Journals@Ovid Ovid Autoload; MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Abdominal surgery. Urology. Gynecology. Obstetrics Adult Anesthesia Anesthesia depending on type of surgery Anesthesia, Obstetrical Anesthesia, Spinal Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Pressure - drug effects Bupivacaine - administration & dosage Cesarean Section Female Heart Rate - drug effects Humans Medical sciences Posture Pregnancy |
| title | Hyperbaric bupivacaine for spinal anesthesia in cesarean section |
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