Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?
Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B ( P < 0.001), skin cho...
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Veröffentlicht in: | Atherosclerosis 1984-09, Vol.52 (3), p.301-307 |
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creator | De Graeve, J. Bouissou, H. Thiers, J.C. Fouet, J. Valdiguié, P. |
description | Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B (
P < 0.001), skin cholesterol (
P < 0.01) and skin apo B (
P < 0.001) levels. Skin apo B is a valuable test because its increase is closely related to the coronary heart disease. From these 2 populations, 2 groups with normal serum apo B (< 1.3 g/1) were selected and compared. No significant differences in the various serum lipids were observed except for triglycerides (
P < 0.05) and serum apo B (
P < 0.05). However, a very significant difference was noticed in the skin apo B (
P < 0.001). With this cutaneous apo B determination it waspossible to foresee coronary heart disease in 75% of patients. This test can be therefore considered useful to predict coronary status. |
doi_str_mv | 10.1016/0021-9150(84)90060-1 |
format | Article |
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P < 0.001), skin cholesterol (
P < 0.01) and skin apo B (
P < 0.001) levels. Skin apo B is a valuable test because its increase is closely related to the coronary heart disease. From these 2 populations, 2 groups with normal serum apo B (< 1.3 g/1) were selected and compared. No significant differences in the various serum lipids were observed except for triglycerides (
P < 0.05) and serum apo B (
P < 0.05). However, a very significant difference was noticed in the skin apo B (
P < 0.001). With this cutaneous apo B determination it waspossible to foresee coronary heart disease in 75% of patients. This test can be therefore considered useful to predict coronary status.]]></description><identifier>ISSN: 0021-9150</identifier><identifier>EISSN: 1879-1484</identifier><identifier>DOI: 10.1016/0021-9150(84)90060-1</identifier><identifier>PMID: 6497934</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Apolipoproteins B - analysis ; Apolipoproteins B - blood ; Arteriosclerosis - blood ; Arteriosclerosis - diagnosis ; Arteriosclerosis - metabolism ; Atherosclerosis ; Cholesterol - analysis ; Coronary Angiography ; Coronary Disease - blood ; Coronary Disease - diagnosis ; Coronary Disease - metabolism ; Coronary Vessels - pathology ; Cutaneous apoprotein B ; Humans ; Lipids - blood ; Male ; Middle Aged ; Serum apoprotein B ; Skin - analysis ; Vascular risk</subject><ispartof>Atherosclerosis, 1984-09, Vol.52 (3), p.301-307</ispartof><rights>1984</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-5cd7d1169021f76324362204526680b306d1c7e8fbe6a22ae7bc68ca6f74383c3</citedby><cites>FETCH-LOGICAL-c357t-5cd7d1169021f76324362204526680b306d1c7e8fbe6a22ae7bc68ca6f74383c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0021-9150(84)90060-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6497934$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>De Graeve, J.</creatorcontrib><creatorcontrib>Bouissou, H.</creatorcontrib><creatorcontrib>Thiers, J.C.</creatorcontrib><creatorcontrib>Fouet, J.</creatorcontrib><creatorcontrib>Valdiguié, P.</creatorcontrib><title>Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?</title><title>Atherosclerosis</title><addtitle>Atherosclerosis</addtitle><description><![CDATA[Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B (
P < 0.001), skin cholesterol (
P < 0.01) and skin apo B (
P < 0.001) levels. Skin apo B is a valuable test because its increase is closely related to the coronary heart disease. From these 2 populations, 2 groups with normal serum apo B (< 1.3 g/1) were selected and compared. No significant differences in the various serum lipids were observed except for triglycerides (
P < 0.05) and serum apo B (
P < 0.05). However, a very significant difference was noticed in the skin apo B (
P < 0.001). With this cutaneous apo B determination it waspossible to foresee coronary heart disease in 75% of patients. This test can be therefore considered useful to predict coronary status.]]></description><subject>Apolipoproteins B - analysis</subject><subject>Apolipoproteins B - blood</subject><subject>Arteriosclerosis - blood</subject><subject>Arteriosclerosis - diagnosis</subject><subject>Arteriosclerosis - metabolism</subject><subject>Atherosclerosis</subject><subject>Cholesterol - analysis</subject><subject>Coronary Angiography</subject><subject>Coronary Disease - blood</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - metabolism</subject><subject>Coronary Vessels - pathology</subject><subject>Cutaneous apoprotein B</subject><subject>Humans</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Serum apoprotein B</subject><subject>Skin - analysis</subject><subject>Vascular risk</subject><issn>0021-9150</issn><issn>1879-1484</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1OwzAQhC0EKqXwBiD5hOAQsGPHdi4gqPipVIkLHJHlOBthlCbFdpB4exxa9cjFe5jZ9cyH0CklV5RQcU1ITrOSFuRC8cuSEEEyuoemVMkyo1zxfTTdWQ7RUQifhBAuqZqgieClLBmfovdFwHaIpoN-CNis-7XvI7gO32ODK4gRPK5dsN6tXGdi73H8MB0O4IcVbt3OH3CTNBM_wPfBtuPrwu0xOmhMG-BkO2fo7fHhdf6cLV-eFvO7ZWZZIWNW2FrWlIoyxW2kYDlnIs8JL3IhFKkYETW1ElRTgTB5bkBWVihrRCM5U8yyGTrf3E1pvgYIUa9SZmjbTS-tKMulKkUy8o3RpoDBQ6PXqZnxP5oSPVLVIzI9ItOK6z-qmqa1s-39oVpBvVvaYkz6zUaHVPLbgdfBOugs1M6Djbru3f8f_AJ0c4b5</recordid><startdate>198409</startdate><enddate>198409</enddate><creator>De Graeve, J.</creator><creator>Bouissou, H.</creator><creator>Thiers, J.C.</creator><creator>Fouet, J.</creator><creator>Valdiguié, P.</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198409</creationdate><title>Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?</title><author>De Graeve, J. ; Bouissou, H. ; Thiers, J.C. ; Fouet, J. ; Valdiguié, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-5cd7d1169021f76324362204526680b306d1c7e8fbe6a22ae7bc68ca6f74383c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Apolipoproteins B - analysis</topic><topic>Apolipoproteins B - blood</topic><topic>Arteriosclerosis - blood</topic><topic>Arteriosclerosis - diagnosis</topic><topic>Arteriosclerosis - metabolism</topic><topic>Atherosclerosis</topic><topic>Cholesterol - analysis</topic><topic>Coronary Angiography</topic><topic>Coronary Disease - blood</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - metabolism</topic><topic>Coronary Vessels - pathology</topic><topic>Cutaneous apoprotein B</topic><topic>Humans</topic><topic>Lipids - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Serum apoprotein B</topic><topic>Skin - analysis</topic><topic>Vascular risk</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>De Graeve, J.</creatorcontrib><creatorcontrib>Bouissou, H.</creatorcontrib><creatorcontrib>Thiers, J.C.</creatorcontrib><creatorcontrib>Fouet, J.</creatorcontrib><creatorcontrib>Valdiguié, P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Atherosclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>De Graeve, J.</au><au>Bouissou, H.</au><au>Thiers, J.C.</au><au>Fouet, J.</au><au>Valdiguié, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?</atitle><jtitle>Atherosclerosis</jtitle><addtitle>Atherosclerosis</addtitle><date>1984-09</date><risdate>1984</risdate><volume>52</volume><issue>3</issue><spage>301</spage><epage>307</epage><pages>301-307</pages><issn>0021-9150</issn><eissn>1879-1484</eissn><abstract><![CDATA[Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B (
P < 0.001), skin cholesterol (
P < 0.01) and skin apo B (
P < 0.001) levels. Skin apo B is a valuable test because its increase is closely related to the coronary heart disease. From these 2 populations, 2 groups with normal serum apo B (< 1.3 g/1) were selected and compared. No significant differences in the various serum lipids were observed except for triglycerides (
P < 0.05) and serum apo B (
P < 0.05). However, a very significant difference was noticed in the skin apo B (
P < 0.001). With this cutaneous apo B determination it waspossible to foresee coronary heart disease in 75% of patients. This test can be therefore considered useful to predict coronary status.]]></abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>6497934</pmid><doi>10.1016/0021-9150(84)90060-1</doi><tpages>7</tpages></addata></record> |
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subjects | Apolipoproteins B - analysis Apolipoproteins B - blood Arteriosclerosis - blood Arteriosclerosis - diagnosis Arteriosclerosis - metabolism Atherosclerosis Cholesterol - analysis Coronary Angiography Coronary Disease - blood Coronary Disease - diagnosis Coronary Disease - metabolism Coronary Vessels - pathology Cutaneous apoprotein B Humans Lipids - blood Male Middle Aged Serum apoprotein B Skin - analysis Vascular risk |
title | Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis? |
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