Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?

Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B ( P < 0.001), skin cho...

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Veröffentlicht in:Atherosclerosis 1984-09, Vol.52 (3), p.301-307
Hauptverfasser: De Graeve, J., Bouissou, H., Thiers, J.C., Fouet, J., Valdiguié, P.
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container_end_page 307
container_issue 3
container_start_page 301
container_title Atherosclerosis
container_volume 52
creator De Graeve, J.
Bouissou, H.
Thiers, J.C.
Fouet, J.
Valdiguié, P.
description Serum lipids, skin apoprotein B (apo B) and skin cholesterol measurements have been investigated in 2 populations: one with normal coronarography, the other with pathological coronarography. Within these 2 populations there were highly significant differences in serum apo B ( P < 0.001), skin cholesterol ( P < 0.01) and skin apo B ( P < 0.001) levels. Skin apo B is a valuable test because its increase is closely related to the coronary heart disease. From these 2 populations, 2 groups with normal serum apo B (< 1.3 g/1) were selected and compared. No significant differences in the various serum lipids were observed except for triglycerides ( P < 0.05) and serum apo B ( P < 0.05). However, a very significant difference was noticed in the skin apo B ( P < 0.001). With this cutaneous apo B determination it waspossible to foresee coronary heart disease in 75% of patients. This test can be therefore considered useful to predict coronary status.
doi_str_mv 10.1016/0021-9150(84)90060-1
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Apolipoproteins B - analysis
Apolipoproteins B - blood
Arteriosclerosis - blood
Arteriosclerosis - diagnosis
Arteriosclerosis - metabolism
Atherosclerosis
Cholesterol - analysis
Coronary Angiography
Coronary Disease - blood
Coronary Disease - diagnosis
Coronary Disease - metabolism
Coronary Vessels - pathology
Cutaneous apoprotein B
Humans
Lipids - blood
Male
Middle Aged
Serum apoprotein B
Skin - analysis
Vascular risk
title Is cutaneous apoprotein B a better discriminator than serum lipoproteins for atherosclerosis?
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