Mechanism of nitroglycerin-induced coronary dilatation: Lack of relation to intracoronary thromboxane concentrations

Intracoronary nitroglycerin (NTG) increases coronary blood flow and NTG inhibits thromboxane (Tx) A 2 production and release. However, whether an alteration in TxA 2 is the mechanism by which NTG increases coronary blood flow is not known. Coronary sinus (CS) blood flow (BF) (by thermodilution) and...

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Veröffentlicht in:	The American journal of cardiology 1984-11, Vol.54 (8), p.971-974
Hauptverfasser:	Rehr, Roger B., Jackson, Jay A., Winniford, Michael D., Campbell, William B., Hillis, L. David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antianginal agents. Coronary vasodilator agents Aspirin - pharmacology Biological and medical sciences Cardiovascular system Coronary Circulation - drug effects Coronary Disease - drug therapy Coronary Disease - physiopathology Coronary Vessels - drug effects Coronary Vessels - physiopathology Female Humans Male Medical sciences Middle Aged Nitroglycerin - pharmacology Nitroglycerin - therapeutic use Pharmacology. Drug treatments Thromboxane A2 - antagonists & inhibitors Thromboxane A2 - blood Thromboxane B2 - antagonists & inhibitors Thromboxane B2 - blood Thromboxanes - antagonists & inhibitors Vasodilation - drug effects
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