Frontal lobe system and spatial reversal in the rat

Ablation of the newly described cortical projection area of the dorsomedial thalamic nucleus impaired spatial reversal retention; ablation of the frontal poles did not. Caudate lesions produced an even stronger reversal deficit. These data extend comparability of effects of prefrontal ablations to t...

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Veröffentlicht in:Neuropsychologia 1971-01, Vol.9 (2), p.175-183
1. Verfasser: Divac, Ivan
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description Ablation of the newly described cortical projection area of the dorsomedial thalamic nucleus impaired spatial reversal retention; ablation of the frontal poles did not. Caudate lesions produced an even stronger reversal deficit. These data extend comparability of effects of prefrontal ablations to the rat and permit the inference of the existence of the system in this species. frontal lobe L'ablation des projections corticales, nouvellement décrites, du noyau thalamique dorso-médian perturbe la rétention du renversement spatial tandis que l'ablation des pôles frontaux ne le fait pas. Les lésions caudées produisent un déficit dans ces épreuves de renversement encore plus accusé. Ces données permettent de comparer les effets des ablations préfontales obtenues chez le rat à ceux obtenués chez les carnivores et les primates. On peut aussi en déduire l'existence d'un systeme du lobe frontal chez le rat. Die Abtragung der kürzlich beschriebenen corticalen Projektion des dorsomedialen Thalamuskernes führt zu einer Beeinträchtigung der räumlichen Umkehr, die Entfernung des Frontalpoles dagegen nicht. Caudatumläsionen verursachen ein stärkeres Umkehrdefizit. Diese Ergebnisse erlauben, Wirkungen von praefrontalen Abtragungen bei Ratten zu vergleichen und zeigen, daβ bei dieser Spezies ein Frontallappensystem vorhanden ist.
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subjects Animals
Behavior, Animal
Caudate Nucleus - physiology
Conditioning (Psychology)
Discrimination Learning
Frontal Lobe - physiology
Memory
Rats
Reinforcement (Psychology)
Reversal Learning
Space Perception
Species Specificity
Thalamic Nuclei - physiology
title Frontal lobe system and spatial reversal in the rat
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