High-frequency variation and population drift in a newly transformed clone of BALB/3T3 cells

During repeated passage of BALB/3T3 cells and testing for anchorage-independent growth, a single transformed clone was isolated from agar, and five subclones were derived from it. These subclones differed from one another in morphology on a solid substratum, efficiency and size of colony formation i...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1984-11, Vol.44 (11), p.5242-5248
Hauptverfasser:	RUBIN, H, ARNSTEIN, P, CHU, B. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Aggregation Cell Division Cell Transformation, Neoplastic Cells, Cultured Clone Cells Culture Techniques - methods Gene Frequency Genetic Variation Medical sciences Mice Mice, Inbred BALB C Mice, Nude Tumor cell Tumors
Online-Zugang:	Volltext
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