$Co-localization of superoxide generation and NADP formation in plasma membrane fractions from human neutrophils$

Co-localization of superoxide generation and NADP formation in plasma membrane fractions from human neutrophils

In order to resolve discrepancies in the literature concerning the subcellular localization of NADPH oxidase, we disrupted human neutrophils by nitrogen cavitation and fractionated the subcellular organelles on a discontinuous sucrose density gradient. The lightest fraction was 20- to 40-fold enrich...

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Veröffentlicht in:	Inflammation 1984-09, Vol.8 (3), p.323-335
Hauptverfasser:	SHIRLEY, P. S, BASS, D. A, LEES, C. J, PARCE, J. W, WAITE, B. M, DECHATELET, L. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Biological and medical sciences Cell Membrane - metabolism Cell physiology Cell Separation - methods Cyanides - pharmacology Endocytosis Fundamental and applied biological sciences. Psychology Glucuronidase - metabolism Humans leukocytes (neutrophilic) man Molecular and cellular biology Muramidase - metabolism NADP NADP - biosynthesis Neutrophils - cytology Neutrophils - enzymology Peroxidase - metabolism Phosphoric Diester Hydrolases - metabolism plasma membranes respiratory burst superoxide Superoxides - biosynthesis
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