Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome
THE acquired immunodeficiency syndrome (AIDS) is a disease of the immune system that results in the development of life-threatening opportunistic infections or unusual neoplasms or both. Although effective therapies exist for many of the infectious and neoplastic complications of this syndrome, no s...
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| Veröffentlicht in: | The New England journal of medicine 1984-10, Vol.311 (17), p.1099-1103 |
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| container_title | The New England journal of medicine |
| container_volume | 311 |
| creator | Lane, H. Clifford Masur, Henry Longo, Dan L Klein, Harvey G Rook, Alain H Quinnan, Gerald V Steis, Ronald G Macher, Abe Whalen, Gail Edgar, Lynn C Fauci, Anthony S |
| description | THE acquired immunodeficiency syndrome (AIDS) is a disease of the immune system that results in the development of life-threatening opportunistic infections or unusual neoplasms or both. Although effective therapies exist for many of the infectious and neoplastic complications of this syndrome, no successful treatment has been developed for the underlying immune defect. Thus, patients are susceptible to recurrent and life-threatening infections and progressive neoplastic processes. The overall mortality in patients with this syndrome remains at approximately 40 per cent. However, since no reversals of the underlying immune dysfunction have reportedly occurred either spontaneously or with therapy, the disease appears to . . . |
| doi_str_mv | 10.1056/NEJM198410253111706 |
| format | Article |
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Clifford ; Masur, Henry ; Longo, Dan L ; Klein, Harvey G ; Rook, Alain H ; Quinnan, Gerald V ; Steis, Ronald G ; Macher, Abe ; Whalen, Gail ; Edgar, Lynn C ; Fauci, Anthony S</creator><creatorcontrib>Lane, H. Clifford ; Masur, Henry ; Longo, Dan L ; Klein, Harvey G ; Rook, Alain H ; Quinnan, Gerald V ; Steis, Ronald G ; Macher, Abe ; Whalen, Gail ; Edgar, Lynn C ; Fauci, Anthony S</creatorcontrib><description>THE acquired immunodeficiency syndrome (AIDS) is a disease of the immune system that results in the development of life-threatening opportunistic infections or unusual neoplasms or both. Although effective therapies exist for many of the infectious and neoplastic complications of this syndrome, no successful treatment has been developed for the underlying immune defect. Thus, patients are susceptible to recurrent and life-threatening infections and progressive neoplastic processes. The overall mortality in patients with this syndrome remains at approximately 40 per cent. However, since no reversals of the underlying immune dysfunction have reportedly occurred either spontaneously or with therapy, the disease appears to . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM198410253111706</identifier><identifier>PMID: 6384784</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Ablation ; Acquired immune deficiency syndrome ; Acquired Immunodeficiency Syndrome - immunology ; Acquired Immunodeficiency Syndrome - therapy ; Adult ; AIDS ; AIDS/HIV ; Antigens ; Biological and medical sciences ; Blood banks ; Blood Transfusion ; Bone Marrow Transplantation ; Case reports ; Cytomegalovirus ; Defects ; Diseases in Twins ; Hemocyanins ; Humans ; Hypersensitivity ; Immune reconstitution ; Immune system ; Immunization, Passive ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunodeficiency ; Immunopathology ; Immunotherapy - methods ; Infections ; Lymphocyte Transfusion ; Lymphocytes ; Male ; Medical sciences ; Neoplasia ; Patients ; Pneumonia ; T-Lymphocytes - immunology ; Transplants & implants ; Tumors</subject><ispartof>The New England journal of medicine, 1984-10, Vol.311 (17), p.1099-1103</ispartof><rights>1985 INIST-CNRS</rights><rights>Copyright Massachusetts Medical Society Oct 25, 1984</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-763e443b567c289f3836445ca69ccb45a5cbf48106d1eeb74574ef3f4125c09b3</citedby><cites>FETCH-LOGICAL-c393t-763e443b567c289f3836445ca69ccb45a5cbf48106d1eeb74574ef3f4125c09b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1876857319?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8902550$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6384784$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lane, H. Clifford</creatorcontrib><creatorcontrib>Masur, Henry</creatorcontrib><creatorcontrib>Longo, Dan L</creatorcontrib><creatorcontrib>Klein, Harvey G</creatorcontrib><creatorcontrib>Rook, Alain H</creatorcontrib><creatorcontrib>Quinnan, Gerald V</creatorcontrib><creatorcontrib>Steis, Ronald G</creatorcontrib><creatorcontrib>Macher, Abe</creatorcontrib><creatorcontrib>Whalen, Gail</creatorcontrib><creatorcontrib>Edgar, Lynn C</creatorcontrib><creatorcontrib>Fauci, Anthony S</creatorcontrib><title>Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>THE acquired immunodeficiency syndrome (AIDS) is a disease of the immune system that results in the development of life-threatening opportunistic infections or unusual neoplasms or both. Although effective therapies exist for many of the infectious and neoplastic complications of this syndrome, no successful treatment has been developed for the underlying immune defect. Thus, patients are susceptible to recurrent and life-threatening infections and progressive neoplastic processes. The overall mortality in patients with this syndrome remains at approximately 40 per cent. However, since no reversals of the underlying immune dysfunction have reportedly occurred either spontaneously or with therapy, the disease appears to . . .</description><subject>Ablation</subject><subject>Acquired immune deficiency syndrome</subject><subject>Acquired Immunodeficiency Syndrome - immunology</subject><subject>Acquired Immunodeficiency Syndrome - therapy</subject><subject>Adult</subject><subject>AIDS</subject><subject>AIDS/HIV</subject><subject>Antigens</subject><subject>Biological and medical sciences</subject><subject>Blood banks</subject><subject>Blood Transfusion</subject><subject>Bone Marrow Transplantation</subject><subject>Case reports</subject><subject>Cytomegalovirus</subject><subject>Defects</subject><subject>Diseases in Twins</subject><subject>Hemocyanins</subject><subject>Humans</subject><subject>Hypersensitivity</subject><subject>Immune reconstitution</subject><subject>Immune system</subject><subject>Immunization, Passive</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunodeficiency</subject><subject>Immunopathology</subject><subject>Immunotherapy - methods</subject><subject>Infections</subject><subject>Lymphocyte Transfusion</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neoplasia</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>T-Lymphocytes - immunology</subject><subject>Transplants & implants</subject><subject>Tumors</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kE9LHTEUxUOx6KvtJyhCQOlGpk0m_5citlqsFW27HTKZO5jHJKNJhvK-vSnv4aKU3s1dnN8593IQek_JR0qE_HRz8fUbNZpT0gpGKVVEvkIrKhhrOCdyD60IaXXDlWEH6E3Oa1KHcrOP9iXTXGm-Qr9ubSreTvgqhCUCvgM3x1x8WYqfI_YRW3xri4dY8G9fHnB5AHzmnhafYNia5gFG7yrhNvh-E4c0B3iLXo92yvButw_Rz88XP84vm-vvX67Oz64bxwwrjZIMOGe9kMq12oxMM8m5cFYa53ourHD9yDUlcqAAveJCcRjZyGkrHDE9O0QftrmPaX5aIJcu-OxgmmyEecmdpq0WrRAVPP4LXM9LivW3jmoltVCMmkqxLeXSnHOCsXtMPti06Sjp_nTe_aPz6jraZS99gOHFsyu56ic73WZnpzHZ6Hx-wbSpWYJU7HSLhZC7COvw36PPwVOURg</recordid><startdate>19841025</startdate><enddate>19841025</enddate><creator>Lane, H. Clifford</creator><creator>Masur, Henry</creator><creator>Longo, Dan L</creator><creator>Klein, Harvey G</creator><creator>Rook, Alain H</creator><creator>Quinnan, Gerald V</creator><creator>Steis, Ronald G</creator><creator>Macher, Abe</creator><creator>Whalen, Gail</creator><creator>Edgar, Lynn C</creator><creator>Fauci, Anthony S</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>19841025</creationdate><title>Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome</title><author>Lane, H. Clifford ; Masur, Henry ; Longo, Dan L ; Klein, Harvey G ; Rook, Alain H ; Quinnan, Gerald V ; Steis, Ronald G ; Macher, Abe ; Whalen, Gail ; Edgar, Lynn C ; Fauci, Anthony S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-763e443b567c289f3836445ca69ccb45a5cbf48106d1eeb74574ef3f4125c09b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Ablation</topic><topic>Acquired immune deficiency syndrome</topic><topic>Acquired Immunodeficiency Syndrome - immunology</topic><topic>Acquired Immunodeficiency Syndrome - therapy</topic><topic>Adult</topic><topic>AIDS</topic><topic>AIDS/HIV</topic><topic>Antigens</topic><topic>Biological and medical sciences</topic><topic>Blood banks</topic><topic>Blood Transfusion</topic><topic>Bone Marrow Transplantation</topic><topic>Case reports</topic><topic>Cytomegalovirus</topic><topic>Defects</topic><topic>Diseases in Twins</topic><topic>Hemocyanins</topic><topic>Humans</topic><topic>Hypersensitivity</topic><topic>Immune reconstitution</topic><topic>Immune system</topic><topic>Immunization, Passive</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunodeficiency</topic><topic>Immunopathology</topic><topic>Immunotherapy - methods</topic><topic>Infections</topic><topic>Lymphocyte Transfusion</topic><topic>Lymphocytes</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neoplasia</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>T-Lymphocytes - immunology</topic><topic>Transplants & implants</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lane, H. 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Clifford</au><au>Masur, Henry</au><au>Longo, Dan L</au><au>Klein, Harvey G</au><au>Rook, Alain H</au><au>Quinnan, Gerald V</au><au>Steis, Ronald G</au><au>Macher, Abe</au><au>Whalen, Gail</au><au>Edgar, Lynn C</au><au>Fauci, Anthony S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1984-10-25</date><risdate>1984</risdate><volume>311</volume><issue>17</issue><spage>1099</spage><epage>1103</epage><pages>1099-1103</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>THE acquired immunodeficiency syndrome (AIDS) is a disease of the immune system that results in the development of life-threatening opportunistic infections or unusual neoplasms or both. Although effective therapies exist for many of the infectious and neoplastic complications of this syndrome, no successful treatment has been developed for the underlying immune defect. Thus, patients are susceptible to recurrent and life-threatening infections and progressive neoplastic processes. The overall mortality in patients with this syndrome remains at approximately 40 per cent. However, since no reversals of the underlying immune dysfunction have reportedly occurred either spontaneously or with therapy, the disease appears to . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>6384784</pmid><doi>10.1056/NEJM198410253111706</doi><tpages>5</tpages></addata></record> |
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| ispartof | The New England journal of medicine, 1984-10, Vol.311 (17), p.1099-1103 |
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| subjects | Ablation Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - immunology Acquired Immunodeficiency Syndrome - therapy Adult AIDS AIDS/HIV Antigens Biological and medical sciences Blood banks Blood Transfusion Bone Marrow Transplantation Case reports Cytomegalovirus Defects Diseases in Twins Hemocyanins Humans Hypersensitivity Immune reconstitution Immune system Immunization, Passive Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunodeficiency Immunopathology Immunotherapy - methods Infections Lymphocyte Transfusion Lymphocytes Male Medical sciences Neoplasia Patients Pneumonia T-Lymphocytes - immunology Transplants & implants Tumors |
| title | Partial Immune Reconstitution in a Patient with the Acquired Immunodeficiency Syndrome |
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