Effects of renal factors on in vitro hepatic cholesterol synthesis in the rat

Two products derived from rat renal tissue have been shown to affect in vitro hepatic cholesterol synthesis. A premevalonate inhibitor of hepatic cholesterol synthesis is associated with the membranes of the renal endoplasmic reticulum. It is stable at −75 C and at 4 C but is heat labile. A pre‐meva...

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Veröffentlicht in:	Lipids 1971-10, Vol.6 (10), p.751-757
Hauptverfasser:	Haven, Guy T., Jacobi, Herbert P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - metabolism Animals Blood Proteins - pharmacology Carbon Isotopes Cattle Cholesterol - biosynthesis Chromatography, Gel Cold Temperature Cytoplasm Endoplasmic Reticulum Hot Temperature In Vitro Techniques Kidney Liver - metabolism Lysosomes Male Mevalonic Acid - metabolism Microsomes Microsomes, Liver - metabolism Molecular Weight Phospholipids - pharmacology Rats Sodium - metabolism Subcellular Fractions
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