Development of plasma 21-deoxycortisol radioimmunoassay and application to the diagnosis of patients with 21-hydroxylase deficiency

Specific 21-deoxycortisol (21-DF) antiserum was raised in New Zealand white rabbits using a 21-DF-3,20-oxime-bovine serum albumin complex. Plasma radioimmunoassay of 21-DF was developed and used together with a radioimmunoassay of 17-hydroxyprogesterone (17-OH-P) for diagnosis of patients with 21-hy...

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Veröffentlicht in:	Journal of steroid biochemistry 1984-01, Vol.21 (2), p.185-191
Hauptverfasser:	Milewicz, A., Vecsei, P., Korth-Schütz, S., Haack, D., Rösler, A., Lichtwald, K., Lewicka, S., Mittelstaedt, G.v.
Format:	Artikel
Sprache:	eng
Schlagworte:	17-alpha-Hydroxyprogesterone 17-Hydroxycorticosteroids - blood Adolescent Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adrenocorticotropic Hormone Adult Biological and medical sciences Child Child, Preschool Clinical Laboratory Techniques Cortodoxone - blood Endocrinopathies Female Hirsutism - blood Humans Hydroxyprogesterones - blood Infant Infant, Newborn Lipid Metabolism, Inborn Errors - blood Lipid Metabolism, Inborn Errors - diagnosis Male Malignant tumors Medical sciences Radioimmunoassay - methods Reference Values Steroid Hydroxylases - deficiency
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