Unstable hemoglobin hemolytic anemia: In vitro incubation studies on erythrocytes with hemoglobin Sabine

Additional biochemical studies have been carried out to investigate the effects of the presence of an unstable hemoglobin (Hb Sabine) on metabolism of erythrocytes. In vitro incubation under physiological conditions of these erythrocytes for periods of 5–15 hours has been utilized to evaluate effect...

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Veröffentlicht in:	Biochemical medicine 1971-06, Vol.5 (3), p.212-226
Hauptverfasser:	Mills, Gordon C., Alperin, Jack B., Hill, Freddie L., Henderson, Ralph J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - pharmacology Adenine Nucleotides - metabolism Anemia, Hemolytic, Congenital - metabolism Azides - pharmacology Chemical Precipitation Disulfides - biosynthesis Erythrocytes - drug effects Erythrocytes - metabolism Globins Glyceraldehyde-3-Phosphate Dehydrogenases - blood Glycerophosphates - metabolism Hemoglobinopathies - metabolism Humans Hypoxanthines - biosynthesis In Vitro Techniques Methylene Blue - pharmacology Nucleotides - metabolism Oxidative Phosphorylation Pyruvates - pharmacology Succinates - pharmacology Time Factors
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