Mechanism of circulatory effects of chlorcyclizine

Intravenous administration of chlorcyclizine produced a biphasic response characterized by an initial and abrupt depressor response followed by a gradual and sustained pressor response. Analysis of this response showed that the initial depressor response was of peripheral origin and was not mediated...

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Veröffentlicht in:	European journal of pharmacology 1971-01, Vol.15 (3), p.386-388
Hauptverfasser:	Sinha, J.N., Shamsi, M.A., Gupta, M.L., Kohli, R.P., Bhargava, K.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Medulla - physiology Animals Biphasic response Blood Circulation - drug effects Blood Pressure - drug effects Cats Chlorcyclizine Female Histamine H1 Antagonists - pharmacology Male Piperazines - pharmacology Sympatho adrenal system
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