Plasmodium berghei: In vitro incorporation of purine derivatives into nucleic acids

Uptake of radioactive adenosine by Plasmodium berghei parasitized erythrocytes is sensitive to competition for uptake over a wide range of concentrations of nonradioactive adenosine. Infection points in the uptake curve for adenosine-8- 3H occur between 10 −4 to 10 −5 and 10 −9 to 10 −10 m nonradioa...

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Veröffentlicht in:	Experimental parasitology 1971-06, Vol.29 (3), p.402-416
Hauptverfasser:	Lantz, C.H., Van Dyke, K., Carter, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	6Mercaptopurine Adenine-8- 3H Adenosine - metabolism Adenosine Diphosphate - metabolism Adenosine Monophosphate - metabolism Adenosine Triphosphate - metabolism Adenosine-3′,5′-cyclic phosphate-8- 3H Adenosine-5′-diphosphate-8- 3H Adenosine-5′-monophosphate-8- 3H Adenosine-5′-triphosphate-8- 3H Adenosine-5′-triphosphate-α- 32P Adenosine-5′-triphosphate-β-γ- 32P Adenosine-8- 3H Animals Biological Transport, Active Cell-Free System Chromatography, paper Competition, metabolic Cyclic AMP-8- 3H Deoxyadenosine-8 3H DNA - biosynthesis DNA polymerase Erythrocytes Guanosine Triphosphate - metabolism Guanosine-5′-triphosphate-8- 3H Hydrogen-Ion Concentration Malaria Metabolism Models, Biological Nucleic acids Nucleic Acids - biosynthesis Nucleosides - metabolism Oxidative Phosphorylation Phosphorus isotopes Plasmodium - metabolism Plasmodium berghei Purines Purines - metabolism Pyrimidines Pyrimidines - metabolism RNA - biosynthesis RNA polymerase RNA, DNA Temperature Tritium
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