Disposition of [ 14C] methyl bromide in fischer-344 rats after oral or intraperitoneal administration

Methyl bromide is used as a disinfectant to fumigate soil. The intent of our study was to determine the diposition of methyl bromide following a single acute administration. Male Fischer-344 rats were given 250 μmol of [ 14C] methyl bromide/kg body wt by either oral or i.p. administration. Urine, fe...

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Veröffentlicht in:	Toxicology (Amsterdam) 1984-01, Vol.32 (3), p.187-196
Hauptverfasser:	Medinsky, M.A., Bond, J.A., Dutcher, J.S., Birnbaum, L.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Bile - analysis Biliary excretion Biological and medical sciences Breath Tests Carbon Dioxide - analysis Disposition Feces - analysis Fischer-344 rats Hydrocarbons, Brominated - administration & dosage Hydrocarbons, Brominated - metabolism Injections, Intraperitoneal Intraperitoneal administration Male Medical sciences Methyl bromide (bromomethane) Oral administration Pesticides, fertilizers and other agrochemicals toxicology Rats Rats, Inbred F344 - metabolism Rats, Inbred Strains - metabolism Time Factors Tissue Distribution Toxicology
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