Autonomic Nerves in the Precapillary Vessel Wall
A wide variety of substances are utilized as neurotransmitters in perivascular autonomic nerves, including noradrenaline, acetylcholine, ATP, 5-hydroxy-tryptamine, and a number of peptides. A general model for the autonomic innervation of the vessel wall is outlined, and variations in the innervatio...
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| Veröffentlicht in: | Journal of cardiovascular pharmacology 1984, Vol.6 Suppl 2, p.S344-S353 |
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| container_end_page | S353 |
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| container_title | Journal of cardiovascular pharmacology |
| container_volume | 6 Suppl 2 |
| creator | Burnstock, G Griffith, S G Sneddon, P |
| description | A wide variety of substances are utilized as neurotransmitters in perivascular autonomic nerves, including noradrenaline, acetylcholine, ATP, 5-hydroxy-tryptamine, and a number of peptides. A general model for the autonomic innervation of the vessel wall is outlined, and variations in the innervation patterns in different precapillary vessels are described. Evidence that noradrenaline and ATP are cotransmitters in some precapillary vessels is presented. In the rat tail artery, ATP appears to be responsible for the fast depolarizations that are recorded in response to perivascular nerve stimulation, whereas noradrenaline is responsible for the slow, maintained depolarization. |
| doi_str_mv | 10.1097/00005344-198406002-00009 |
| format | Article |
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A general model for the autonomic innervation of the vessel wall is outlined, and variations in the innervation patterns in different precapillary vessels are described. Evidence that noradrenaline and ATP are cotransmitters in some precapillary vessels is presented. 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A general model for the autonomic innervation of the vessel wall is outlined, and variations in the innervation patterns in different precapillary vessels are described. Evidence that noradrenaline and ATP are cotransmitters in some precapillary vessels is presented. In the rat tail artery, ATP appears to be responsible for the fast depolarizations that are recorded in response to perivascular nerve stimulation, whereas noradrenaline is responsible for the slow, maintained depolarization.</description><subject>Acetylcholine - physiology</subject><subject>Animals</subject><subject>Arterioles - physiology</subject><subject>Autonomic Nervous System - physiology</subject><subject>Humans</subject><subject>Microcirculation - innervation</subject><subject>Muscle, Smooth, Vascular - innervation</subject><subject>Neuroeffector Junction - physiology</subject><subject>Neurotransmitter Agents - physiology</subject><subject>Norepinephrine - physiology</subject><subject>Synaptic Transmission</subject><issn>0160-2446</issn><issn>1533-4023</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UctOwzAQtBColMInIOXELbCOHcc-VhUvqQIOPI6W7WzUgNMUO6Hi70lp6Y29rDSzszuaJSShcElBFVcwVM44T6mSHARAlm4gdUDGNGcs5ZCxQzIGKiDNOBfH5CTGdwDK80KMyEhkIBhnYwLTvmuXbVO75AHDF8akXibdApOngM6sau9N-E5eMUb0yZvx_pQcVcZHPNv1CXm5uX6e3aXzx9v72XSeOg65Spk1SkpjqxJoSa3LjTDgLC-ZKEXFwTpUilInsbA8Z8ZxafIilyXYQgqkbEIutntXof3sMXa6qaPDwc8S2z5qSbOMKQHDoNwOutDGGLDSq1A3g2tNQW_C0n9h6X1Yv5AapOe7G71tsNwLd-kMPN_y69Z3GOKH79cY9AKN7xb6vx-wH7F5cz8</recordid><startdate>1984</startdate><enddate>1984</enddate><creator>Burnstock, G</creator><creator>Griffith, S G</creator><creator>Sneddon, P</creator><general>Lippincott-Raven Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1984</creationdate><title>Autonomic Nerves in the Precapillary Vessel Wall</title><author>Burnstock, G ; Griffith, S G ; Sneddon, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4059-3ba988abfd01d1bc5a6a0cb4d36d6f40bce9911c8e7b453ac48a5758d0b786e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Acetylcholine - physiology</topic><topic>Animals</topic><topic>Arterioles - physiology</topic><topic>Autonomic Nervous System - physiology</topic><topic>Humans</topic><topic>Microcirculation - innervation</topic><topic>Muscle, Smooth, Vascular - innervation</topic><topic>Neuroeffector Junction - physiology</topic><topic>Neurotransmitter Agents - physiology</topic><topic>Norepinephrine - physiology</topic><topic>Synaptic Transmission</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burnstock, G</creatorcontrib><creatorcontrib>Griffith, S G</creatorcontrib><creatorcontrib>Sneddon, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiovascular pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burnstock, G</au><au>Griffith, S G</au><au>Sneddon, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Autonomic Nerves in the Precapillary Vessel Wall</atitle><jtitle>Journal of cardiovascular pharmacology</jtitle><addtitle>J Cardiovasc Pharmacol</addtitle><date>1984</date><risdate>1984</risdate><volume>6 Suppl 2</volume><spage>S344</spage><epage>S353</epage><pages>S344-S353</pages><issn>0160-2446</issn><eissn>1533-4023</eissn><abstract>A wide variety of substances are utilized as neurotransmitters in perivascular autonomic nerves, including noradrenaline, acetylcholine, ATP, 5-hydroxy-tryptamine, and a number of peptides. 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| ispartof | Journal of cardiovascular pharmacology, 1984, Vol.6 Suppl 2, p.S344-S353 |
| issn | 0160-2446 1533-4023 |
| language | eng |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Acetylcholine - physiology Animals Arterioles - physiology Autonomic Nervous System - physiology Humans Microcirculation - innervation Muscle, Smooth, Vascular - innervation Neuroeffector Junction - physiology Neurotransmitter Agents - physiology Norepinephrine - physiology Synaptic Transmission |
| title | Autonomic Nerves in the Precapillary Vessel Wall |
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