Transcription factors ETF, E2F, and SP‐1 are involved in cytokine‐independent proliferation of murine hepatocytes

The cellular basis of liver regeneration has been intensely investigated for many years. However, the mechanisms initiating hepatocyte “plasticity” and priming for proliferation are not yet fully clear. We investigated alterations in gene expression patterns during the first 72 hours of C57BL/6N mou...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2010-12, Vol.52 (6), p.2127-2136
Hauptverfasser:	Zellmer, Sebastian, Schmidt‐Heck, Wolfgang, Godoy, Patricio, Weng, Honglei, Meyer, Christoph, Lehmann, Thomas, Sparna, Titus, Schormann, Wiebke, Hammad, Seddik, Kreutz, Clemens, Timmer, Jens, von Weizsäcker, Fritz, Thürmann, Petra A., Merfort, Irmgard, Guthke, Reinhard, Dooley, Steven, Hengstler, Jan G., Gebhardt, Rolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites - physiology Biological and medical sciences Carbon Tetrachloride Poisoning - physiopathology Cell Proliferation Cytokines DNA-Binding Proteins - physiology E2F1 Transcription Factor - physiology Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Hepatectomy Hepatocytes - cytology Hepatology Kinases Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Mice Mice, Inbred C57BL Mitogen-Activated Protein Kinase 1 - physiology Mitogen-Activated Protein Kinase 3 - physiology Rodents Signal Transduction - drug effects Sp1 Transcription Factor - physiology Transcription factors Transcription Factors - physiology Up-Regulation
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