Sustained protection from pentavalent rotavirus vaccination during the second year of life at a large, urban United States pediatric hospital

Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effect...

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Veröffentlicht in:The Pediatric infectious disease journal 2010-12, Vol.29 (12), p.1133-1135
Hauptverfasser: Boom, Julie A, Tate, Jacqueline E, Sahni, Leila C, Rench, Marcia A, Quaye, Osbourne, Mijatovic-Rustempasic, Slavica, Patel, Manish M, Baker, Carol J, Parashar, Umesh D
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container_end_page 1135
container_issue 12
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container_title The Pediatric infectious disease journal
container_volume 29
creator Boom, Julie A
Tate, Jacqueline E
Sahni, Leila C
Rench, Marcia A
Quaye, Osbourne
Mijatovic-Rustempasic, Slavica
Patel, Manish M
Baker, Carol J
Parashar, Umesh D
description Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children ≥12 months of age.
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subjects Age Factors
Feces - virology
Gastroenteritis - epidemiology
Gastroenteritis - prevention & control
Gastroenteritis - virology
Hospitals, Pediatric
Humans
Infant
Infant, Newborn
Rotavirus Infections - epidemiology
Rotavirus Infections - immunology
Rotavirus Infections - prevention & control
Rotavirus Vaccines - immunology
Texas
Urban Population
Vaccines, Attenuated - immunology
title Sustained protection from pentavalent rotavirus vaccination during the second year of life at a large, urban United States pediatric hospital
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