Safety and tolerability of lersivirine, a nonnucleoside reverse transcriptase inhibitor, during a 28-day, randomized, placebo-controlled, Phase I clinical study in healthy male volunteers

Abstract Background: Lersivirine is a nonnucleoside reverse transcriptase inhibitor undergoing clinical development for the treatment of HIV-1. Objective: The goal of this study was to investigate the safety and tolerability of multiple oral doses of lersivirine administered to healthy male subjects...

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Veröffentlicht in:Clinical therapeutics 2010-10, Vol.32 (11), p.1889-1895
Hauptverfasser: Davis, John, PhD, Hackman, Frances, MSc, Ndongo, Marie-Noella, MD, Choo, HengWee, MD, Lewis, Drew, MD, Tawadrous, Margaret, MD, Goodrich, James, PhD, MD, Langdon, Grant, PhD
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Sprache:eng
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