Structure of Daunomycin; X-ray Analysis of N-Br-Acetyl-Daunomycin Solvate

THE antibiotic daunomycin was discovered and studied by Di Marco and co-workers1-5 who found it to have cytotoxic and antimitotic activity. Extensive chemical work by Arca-mone and co-workers6-9 has established the total absolute configuration as in Fig. 1, which gives the formula of the N-Br-acetyl...

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Veröffentlicht in:Nature. New biology (London) 1971-11, Vol.234 (46), p.78-80
Hauptverfasser: ANGIULI, R, FORESTI, E, SANSEVERINO, L. RIVA DI, ISAACS, N. W, KENNARD, O, MOTHERWELL, W. D. S, WAMPLER, D. L, ARCAMONE, F
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