Acute necrosis of the intestinal mucosa with high serum levels of diamine oxidase
A patient with acute necrosis of the intestinal mucosa and high serum diamine oxidase activity is described. The 71-year-old woman, with a history of hypertension and cardiovascular and peripheral arteriosclerotic disease, presented with acute epigastric pain, vomiting, and a deteriorating hemodynam...
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Veröffentlicht in: | Digestive diseases and sciences 1984-09, Vol.29 (9), p.872-874 |
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creator | BOUNOUS, G ECHAVE, V VOBECKY, S. J NAVERT, H WOLLIN, A |
description | A patient with acute necrosis of the intestinal mucosa and high serum diamine oxidase activity is described. The 71-year-old woman, with a history of hypertension and cardiovascular and peripheral arteriosclerotic disease, presented with acute epigastric pain, vomiting, and a deteriorating hemodynamic condition. Serum level of the intestinal enzyme diamine oxidase (DAO) obtained on admission, approximately 24 hr after the onset of symptoms, was 7.4 times above the normal value. An exploratory laparotomy performed 6 hr later revealed cyanosis and areas of transmural necrosis involving the entire small bowel. The bowel was not resected because of the extent of lesion. Thirty hours after the first sample was taken and 2 hr before death, the serum DAO level was only slightly above normal. It is suggested that this biochemical marker could provide a valuable tool for the early diagnosis of intestinal ischemia. |
doi_str_mv | 10.1007/BF01318436 |
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J ; NAVERT, H ; WOLLIN, A</creator><creatorcontrib>BOUNOUS, G ; ECHAVE, V ; VOBECKY, S. J ; NAVERT, H ; WOLLIN, A</creatorcontrib><description>A patient with acute necrosis of the intestinal mucosa and high serum diamine oxidase activity is described. The 71-year-old woman, with a history of hypertension and cardiovascular and peripheral arteriosclerotic disease, presented with acute epigastric pain, vomiting, and a deteriorating hemodynamic condition. Serum level of the intestinal enzyme diamine oxidase (DAO) obtained on admission, approximately 24 hr after the onset of symptoms, was 7.4 times above the normal value. An exploratory laparotomy performed 6 hr later revealed cyanosis and areas of transmural necrosis involving the entire small bowel. The bowel was not resected because of the extent of lesion. Thirty hours after the first sample was taken and 2 hr before death, the serum DAO level was only slightly above normal. It is suggested that this biochemical marker could provide a valuable tool for the early diagnosis of intestinal ischemia.</description><identifier>ISSN: 0163-2116</identifier><identifier>EISSN: 1573-2568</identifier><identifier>DOI: 10.1007/BF01318436</identifier><identifier>PMID: 6432501</identifier><identifier>CODEN: DDSCDJ</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Acute Disease ; Aged ; Amine Oxidase (Copper-Containing) - blood ; Biological and medical sciences ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Intestinal Mucosa - blood supply ; Intestinal Mucosa - pathology ; Ischemia - blood ; Ischemia - diagnosis ; Medical sciences ; Necrosis - diagnosis ; Other diseases. Semiology ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>Digestive diseases and sciences, 1984-09, Vol.29 (9), p.872-874</ispartof><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-f462ab40e9cadb3ecf21588119d8051b73c517b4e280f80e831deb59bbbb5fff3</citedby><cites>FETCH-LOGICAL-c352t-f462ab40e9cadb3ecf21588119d8051b73c517b4e280f80e831deb59bbbb5fff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8968628$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6432501$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BOUNOUS, G</creatorcontrib><creatorcontrib>ECHAVE, V</creatorcontrib><creatorcontrib>VOBECKY, S. J</creatorcontrib><creatorcontrib>NAVERT, H</creatorcontrib><creatorcontrib>WOLLIN, A</creatorcontrib><title>Acute necrosis of the intestinal mucosa with high serum levels of diamine oxidase</title><title>Digestive diseases and sciences</title><addtitle>Dig Dis Sci</addtitle><description>A patient with acute necrosis of the intestinal mucosa and high serum diamine oxidase activity is described. The 71-year-old woman, with a history of hypertension and cardiovascular and peripheral arteriosclerotic disease, presented with acute epigastric pain, vomiting, and a deteriorating hemodynamic condition. Serum level of the intestinal enzyme diamine oxidase (DAO) obtained on admission, approximately 24 hr after the onset of symptoms, was 7.4 times above the normal value. An exploratory laparotomy performed 6 hr later revealed cyanosis and areas of transmural necrosis involving the entire small bowel. The bowel was not resected because of the extent of lesion. Thirty hours after the first sample was taken and 2 hr before death, the serum DAO level was only slightly above normal. It is suggested that this biochemical marker could provide a valuable tool for the early diagnosis of intestinal ischemia.</description><subject>Acute Disease</subject><subject>Aged</subject><subject>Amine Oxidase (Copper-Containing) - blood</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Intestinal Mucosa - blood supply</subject><subject>Intestinal Mucosa - pathology</subject><subject>Ischemia - blood</subject><subject>Ischemia - diagnosis</subject><subject>Medical sciences</subject><subject>Necrosis - diagnosis</subject><subject>Other diseases. Semiology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Abdomen</topic><topic>Humans</topic><topic>Intestinal Mucosa - blood supply</topic><topic>Intestinal Mucosa - pathology</topic><topic>Ischemia - blood</topic><topic>Ischemia - diagnosis</topic><topic>Medical sciences</topic><topic>Necrosis - diagnosis</topic><topic>Other diseases. Semiology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BOUNOUS, G</creatorcontrib><creatorcontrib>ECHAVE, V</creatorcontrib><creatorcontrib>VOBECKY, S. J</creatorcontrib><creatorcontrib>NAVERT, H</creatorcontrib><creatorcontrib>WOLLIN, A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Digestive diseases and sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BOUNOUS, G</au><au>ECHAVE, V</au><au>VOBECKY, S. 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An exploratory laparotomy performed 6 hr later revealed cyanosis and areas of transmural necrosis involving the entire small bowel. The bowel was not resected because of the extent of lesion. Thirty hours after the first sample was taken and 2 hr before death, the serum DAO level was only slightly above normal. It is suggested that this biochemical marker could provide a valuable tool for the early diagnosis of intestinal ischemia.</abstract><cop>Heidelberg</cop><pub>Springer</pub><pmid>6432501</pmid><doi>10.1007/BF01318436</doi><tpages>3</tpages></addata></record> |
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subjects | Acute Disease Aged Amine Oxidase (Copper-Containing) - blood Biological and medical sciences Female Gastroenterology. Liver. Pancreas. Abdomen Humans Intestinal Mucosa - blood supply Intestinal Mucosa - pathology Ischemia - blood Ischemia - diagnosis Medical sciences Necrosis - diagnosis Other diseases. Semiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
title | Acute necrosis of the intestinal mucosa with high serum levels of diamine oxidase |
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