Cerebral blastomycosis: an immunodiagnostic study
Cerebral blastomycosis may simulate a brain tumor. Its diagnosis is sometimes very difficult. The morphologic identification of the fungus may be misleading because it shares some common features with many other dimorphic fungi. Culturing and conversion of the organism from mycelial phase to yeast p...
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Veröffentlicht in: | American journal of clinical pathology 1984-08, Vol.82 (2), p.243-246 |
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container_title | American journal of clinical pathology |
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creator | TANG, T. T MARSIK, F. J HARB, J. M WILLIAMS, J. E FROMMELL, G. T DUNN, D. K |
description | Cerebral blastomycosis may simulate a brain tumor. Its diagnosis is sometimes very difficult. The morphologic identification of the fungus may be misleading because it shares some common features with many other dimorphic fungi. Culturing and conversion of the organism from mycelial phase to yeast phase are not always successful. Immunofluorescent staining of the biopsy tissue is useful in confirming the diagnosis. However, a combination of double immunodiffusion (DID) test and complement fixation (CF) test makes the diagnosis more accurate and reliable. The direct role of macrophages in defending the host against blastomycosis is illustrated by electron microscopy. |
doi_str_mv | 10.1093/ajcp/82.2.243 |
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The direct role of macrophages in defending the host against blastomycosis is illustrated by electron microscopy.</description><subject>Antigens, Fungal - analysis</subject><subject>Biological and medical sciences</subject><subject>Blastomyces - immunology</subject><subject>Blastomyces - ultrastructure</subject><subject>Blastomycosis - diagnosis</subject><subject>Blastomycosis - pathology</subject><subject>Brain Abscess - diagnosis</subject><subject>Brain Abscess - pathology</subject><subject>Brain Neoplasms - diagnosis</subject><subject>Child</subject><subject>Diagnosis, Differential</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous mycoses</subject><subject>Mycoses</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtrwzAUhUVpSdO0Y8eCh9LNia4eltythPQBgS7tLK5lqTj4kUr2kH9fh5is5cC9w_k4w0fIPdAl0JyvcGf3K82WYwS_IHPIBU-VYuySzCmlLM1B8WtyE-OOUmCaihmZZSKTNIc5gbULrghYJ0WNse-ag-1iFZ8TbJOqaYa2Kyv8abvYVzaJ_VAebsmVxzq6u-kvyPfr5mv9nm4_3z7WL9vUcqH7VAl0IMejJXIlMsVBg8UiY6WVHjz6TCB3HCCXBadlJnPtqXWF9xqkV3xBnk67-9D9Di72pqmidXWNreuGaDSAVgyyf0EQoJjQcgTTE2hDF2Nw3uxD1WA4GKDm6NIcXRrNzBjBR_5hGh6KxpVnepI39o9Tj9Fi7QO2topnTOeUjSj_A6BRfAA</recordid><startdate>198408</startdate><enddate>198408</enddate><creator>TANG, T. T</creator><creator>MARSIK, F. J</creator><creator>HARB, J. M</creator><creator>WILLIAMS, J. E</creator><creator>FROMMELL, G. T</creator><creator>DUNN, D. K</creator><general>American Society of Clinical Pathologists</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>198408</creationdate><title>Cerebral blastomycosis: an immunodiagnostic study</title><author>TANG, T. T ; MARSIK, F. J ; HARB, J. M ; WILLIAMS, J. E ; FROMMELL, G. T ; DUNN, D. K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c348t-74ae154ae85a374673181cab62dc5f1faf64a3e31195b30d6598f0cebff815f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Antigens, Fungal - analysis</topic><topic>Biological and medical sciences</topic><topic>Blastomyces - immunology</topic><topic>Blastomyces - ultrastructure</topic><topic>Blastomycosis - diagnosis</topic><topic>Blastomycosis - pathology</topic><topic>Brain Abscess - diagnosis</topic><topic>Brain Abscess - pathology</topic><topic>Brain Neoplasms - diagnosis</topic><topic>Child</topic><topic>Diagnosis, Differential</topic><topic>Human mycoses</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous mycoses</topic><topic>Mycoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TANG, T. T</creatorcontrib><creatorcontrib>MARSIK, F. J</creatorcontrib><creatorcontrib>HARB, J. M</creatorcontrib><creatorcontrib>WILLIAMS, J. E</creatorcontrib><creatorcontrib>FROMMELL, G. T</creatorcontrib><creatorcontrib>DUNN, D. K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TANG, T. T</au><au>MARSIK, F. J</au><au>HARB, J. M</au><au>WILLIAMS, J. E</au><au>FROMMELL, G. T</au><au>DUNN, D. K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral blastomycosis: an immunodiagnostic study</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>1984-08</date><risdate>1984</risdate><volume>82</volume><issue>2</issue><spage>243</spage><epage>246</epage><pages>243-246</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><coden>AJCPAI</coden><abstract>Cerebral blastomycosis may simulate a brain tumor. Its diagnosis is sometimes very difficult. The morphologic identification of the fungus may be misleading because it shares some common features with many other dimorphic fungi. Culturing and conversion of the organism from mycelial phase to yeast phase are not always successful. Immunofluorescent staining of the biopsy tissue is useful in confirming the diagnosis. However, a combination of double immunodiffusion (DID) test and complement fixation (CF) test makes the diagnosis more accurate and reliable. The direct role of macrophages in defending the host against blastomycosis is illustrated by electron microscopy.</abstract><cop>Chicago, IL</cop><pub>American Society of Clinical Pathologists</pub><pmid>6465091</pmid><doi>10.1093/ajcp/82.2.243</doi><tpages>4</tpages></addata></record> |
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subjects | Antigens, Fungal - analysis Biological and medical sciences Blastomyces - immunology Blastomyces - ultrastructure Blastomycosis - diagnosis Blastomycosis - pathology Brain Abscess - diagnosis Brain Abscess - pathology Brain Neoplasms - diagnosis Child Diagnosis, Differential Human mycoses Humans Infectious diseases Male Medical sciences Miscellaneous mycoses Mycoses |
title | Cerebral blastomycosis: an immunodiagnostic study |
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