Mendelian and Uniparental Alterations in Erythromycin Binding by Plastid Ribosomes

Erythromycin binds specifically to the 52S subunit of the chloroplast ribosome of Chlamydomonas reinhardi. A number of erythromycin-resistant mutants whose ribosomes have lost their affinity for the antibiotic have been isolated, but the sedimentation properties of their ribosomes are indistinguisha...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1971-11, Vol.174 (4010), p.707-709
Hauptverfasser:	Mets, Laurens J., Bogorad, Lawrence
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Carbon Isotopes Cell Fractionation Centrifugation, Density Gradient Chlorophyta - metabolism Chloroplasts Chloroplasts - metabolism Crosses, Genetic Drug Resistance, Microbial Erythromycin - metabolism Erythromycin - pharmacology Eukaryota - drug effects Genetic loci Genetic mutation Genetics, Microbial Muscle fibers Mutation Nucleic acids Plant cells Ribosomes Ribosomes - metabolism RNA
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