A New Animal Model for Human Respiratory Tract Disease Due to Adenovirus

Cotton rats (Sigmodon hispidus) were tested as a model for human respiratory tract infection due to adenovirus. After intranasal instillation of 106.1 50% tissue culture infectious doses (TCID50) of adenovirus type 5 into one-month-old cotton rats, groups were killed at intervals for nasal and lung...

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Veröffentlicht in:	The Journal of infectious diseases 1984-07, Vol.150 (1), p.92-97
Hauptverfasser:	Pacini, David L., Dubovi, Edward J., Clyde, Wallace A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Infections - microbiology Adenoviridae Infections - pathology Adenovirus Infections, Human - microbiology Adenovirus Infections, Human - pathology Adenoviruses Adenoviruses, Human - growth & development Adenoviruses, Human - immunology Animal models Animals Antibodies, Viral - analysis Arvicolinae Biological and medical sciences Disease models Disease Models, Animal Diseases Experimental viral diseases and models Humans Infections Infectious diseases Lung - microbiology Lung - pathology Lung Diseases - microbiology Lung Diseases - pathology Lungs Medical sciences Neutralization Tests Original Articles Pulmonary Alveoli - pathology Rats Respiratory Tract Infections - microbiology Respiratory Tract Infections - pathology Viral diseases Viruses
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