Human T cell clones exerting multiple cytolytic activities show heterogeneity in susceptibility to inhibition by monoclonal antibodies

Human cytotoxic T cell clones (CTL) were obtained by limiting dilution after in vitro priming against an allogeneic Epstein Barr virus (EBV)-transformed B cell line (B-LCL) BSM. Three OKT3+, OKT8+ E rosette-forming (RFC) but EA gamma-RFC- clones with cytotoxic activity against the stimulator cell an...

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Veröffentlicht in:	The Journal of immunology (1950) 1984-09, Vol.133 (3), p.1222-1229
Hauptverfasser:	van de Griend, RJ, Giphart, MJ, Van Krimpen, BA, Bolhuis, RL
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Antibodies, Monoclonal - physiology Antigens, Surface - immunology Binding, Competitive Biological and medical sciences Clone Cells - classification Clone Cells - immunology Cytotoxicity, Immunologic Epitopes Fundamental and applied biological sciences. Psychology Fundamental immunology HLA Antigens - immunology Humans Immunobiology Lymphocyte Activation Organs and cells involved in the immune response Phenotype Phytohemagglutinins - pharmacology T-Lymphocytes, Cytotoxic - classification T-Lymphocytes, Cytotoxic - immunology
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