Therapy of Ischemic Cerebral Vascular Disease Due to Atherothrombosis
Therapy for Transient Ischemic Attacks Surgical Therapy Carotid endarterectomy remains the mainstay of the therapy for TIAs that are caused by carotid stenosis. First introduced in 1954 by Eastcott et al., 104 the procedure has been associated with a morbidity ranging from 1 to 20 per cent, dependin...
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| Veröffentlicht in: | The New England journal of medicine 1984-07, Vol.311 (2), p.100-105 |
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| container_title | The New England journal of medicine |
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| creator | Kistler, J. Philip Ropper, Allan H Heros, Roberto C |
| description | Therapy for Transient Ischemic Attacks
Surgical Therapy
Carotid endarterectomy remains the mainstay of the therapy for TIAs that are caused by carotid stenosis. First introduced in 1954 by Eastcott et al.,
104
the procedure has been associated with a morbidity ranging from 1 to 20 per cent, depending largely on the patient population and the experience of the surgeon.
42,55,
105
106
107
108
109
Although many studies suggest that this procedure is effective in preventing additional TIAs or strokes,
55,
105
106
107
,
109
,
110
its value is yet to be confirmed by a well-designed, controlled, randomized clinical trial. In the one multicenter controlled study published thus far, 24 centers randomly assigned . . . |
| doi_str_mv | 10.1056/NEJM198407123110206 |
| format | Article |
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Surgical Therapy
Carotid endarterectomy remains the mainstay of the therapy for TIAs that are caused by carotid stenosis. First introduced in 1954 by Eastcott et al.,
104
the procedure has been associated with a morbidity ranging from 1 to 20 per cent, depending largely on the patient population and the experience of the surgeon.
42,55,
105
106
107
108
109
Although many studies suggest that this procedure is effective in preventing additional TIAs or strokes,
55,
105
106
107
,
109
,
110
its value is yet to be confirmed by a well-designed, controlled, randomized clinical trial. In the one multicenter controlled study published thus far, 24 centers randomly assigned . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM198407123110206</identifier><identifier>PMID: 6377062</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Anticoagulants ; Anticoagulants - therapeutic use ; Arterial Occlusive Diseases - drug therapy ; Aspirin - therapeutic use ; Auscultation ; Basilar Artery ; Blood Platelets - drug effects ; Blood pressure ; Carotid arteries ; Carotid Arteries - physiopathology ; Carotid artery ; Carotid Artery Diseases - diagnosis ; Carotid Artery Diseases - therapy ; Cerebral Arteries - surgery ; Cerebrovascular Disorders - drug therapy ; Cerebrovascular Disorders - surgery ; Cerebrovascular Disorders - therapy ; Dipyridamole - therapeutic use ; Endarterectomy ; Heart surgery ; Humans ; Hypertension ; Intracranial Arteriosclerosis - complications ; Ischemia ; Ischemic Attack, Transient - drug therapy ; Medical imaging ; Morbidity ; Neurology ; Neurosurgery ; Patients ; Stroke ; Surgeons ; Ulcers ; Vascular diseases ; Veins & arteries ; Vertebral Artery</subject><ispartof>The New England journal of medicine, 1984-07, Vol.311 (2), p.100-105</ispartof><rights>Copyright Massachusetts Medical Society Jul 12, 1984</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c279t-88b0f973dd56b1cd2ad5117550dcc0efdb06f67e872f9548aa08814340e190363</citedby><cites>FETCH-LOGICAL-c279t-88b0f973dd56b1cd2ad5117550dcc0efdb06f67e872f9548aa08814340e190363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1876855304?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6377062$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kistler, J. Philip</creatorcontrib><creatorcontrib>Ropper, Allan H</creatorcontrib><creatorcontrib>Heros, Roberto C</creatorcontrib><title>Therapy of Ischemic Cerebral Vascular Disease Due to Atherothrombosis</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Therapy for Transient Ischemic Attacks
Surgical Therapy
Carotid endarterectomy remains the mainstay of the therapy for TIAs that are caused by carotid stenosis. First introduced in 1954 by Eastcott et al.,
104
the procedure has been associated with a morbidity ranging from 1 to 20 per cent, depending largely on the patient population and the experience of the surgeon.
42,55,
105
106
107
108
109
Although many studies suggest that this procedure is effective in preventing additional TIAs or strokes,
55,
105
106
107
,
109
,
110
its value is yet to be confirmed by a well-designed, controlled, randomized clinical trial. In the one multicenter controlled study published thus far, 24 centers randomly assigned . . .</description><subject>Anticoagulants</subject><subject>Anticoagulants - therapeutic use</subject><subject>Arterial Occlusive Diseases - drug therapy</subject><subject>Aspirin - therapeutic use</subject><subject>Auscultation</subject><subject>Basilar Artery</subject><subject>Blood Platelets - drug effects</subject><subject>Blood pressure</subject><subject>Carotid arteries</subject><subject>Carotid Arteries - physiopathology</subject><subject>Carotid artery</subject><subject>Carotid Artery Diseases - diagnosis</subject><subject>Carotid Artery Diseases - therapy</subject><subject>Cerebral Arteries - surgery</subject><subject>Cerebrovascular Disorders - drug therapy</subject><subject>Cerebrovascular Disorders - surgery</subject><subject>Cerebrovascular Disorders - therapy</subject><subject>Dipyridamole - therapeutic use</subject><subject>Endarterectomy</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Intracranial Arteriosclerosis - complications</subject><subject>Ischemia</subject><subject>Ischemic Attack, Transient - drug therapy</subject><subject>Medical imaging</subject><subject>Morbidity</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Patients</subject><subject>Stroke</subject><subject>Surgeons</subject><subject>Ulcers</subject><subject>Vascular diseases</subject><subject>Veins & arteries</subject><subject>Vertebral Artery</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kEtLxEAQhAdRdH38AhECgheJdmeeOcq6vvBxUa9hMumwWZKddSY5-O-N7OJBxL7Uob4qmmLsGOECQarL59nDE-ZGgMaMI0IGaotNUHKeCgFqm00AMpMKnfM9th_jAsZDke-yXcW1BpVN2Ox1TsGuPhNfJ_fRzalrXDKlQGWwbfJuoxtaG5LrJpKNlFwPlPQ-uerHlO_nwXelj008ZDu1bSMdbfSAvd3MXqd36ePL7f306jF1mc771JgS6lzzqpKqRFdltpKIWkqonAOqqxJUrTQZndW5FMZaMAYFF0CYA1f8gJ2te1fBfwwU-6JroqO2tUvyQywMIhcK9Aie_gIXfgjL8bcCjVZGSg5ipPiacsHHGKguVqHpbPgsEIrviYs_Jh5TJ5vuoeyo-slsNh3987XfdbFY0qL7t-0LMVGArw</recordid><startdate>19840712</startdate><enddate>19840712</enddate><creator>Kistler, J. 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Philip ; Ropper, Allan H ; Heros, Roberto C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c279t-88b0f973dd56b1cd2ad5117550dcc0efdb06f67e872f9548aa08814340e190363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Anticoagulants</topic><topic>Anticoagulants - therapeutic use</topic><topic>Arterial Occlusive Diseases - drug therapy</topic><topic>Aspirin - therapeutic use</topic><topic>Auscultation</topic><topic>Basilar Artery</topic><topic>Blood Platelets - drug effects</topic><topic>Blood pressure</topic><topic>Carotid arteries</topic><topic>Carotid Arteries - physiopathology</topic><topic>Carotid artery</topic><topic>Carotid Artery Diseases - diagnosis</topic><topic>Carotid Artery Diseases - therapy</topic><topic>Cerebral Arteries - surgery</topic><topic>Cerebrovascular Disorders - drug therapy</topic><topic>Cerebrovascular Disorders - surgery</topic><topic>Cerebrovascular Disorders - therapy</topic><topic>Dipyridamole - therapeutic use</topic><topic>Endarterectomy</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Intracranial Arteriosclerosis - complications</topic><topic>Ischemia</topic><topic>Ischemic Attack, Transient - drug therapy</topic><topic>Medical imaging</topic><topic>Morbidity</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>Patients</topic><topic>Stroke</topic><topic>Surgeons</topic><topic>Ulcers</topic><topic>Vascular diseases</topic><topic>Veins & arteries</topic><topic>Vertebral Artery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kistler, J. Philip</creatorcontrib><creatorcontrib>Ropper, Allan H</creatorcontrib><creatorcontrib>Heros, Roberto C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kistler, J. Philip</au><au>Ropper, Allan H</au><au>Heros, Roberto C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapy of Ischemic Cerebral Vascular Disease Due to Atherothrombosis</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1984-07-12</date><risdate>1984</risdate><volume>311</volume><issue>2</issue><spage>100</spage><epage>105</epage><pages>100-105</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>Therapy for Transient Ischemic Attacks
Surgical Therapy
Carotid endarterectomy remains the mainstay of the therapy for TIAs that are caused by carotid stenosis. First introduced in 1954 by Eastcott et al.,
104
the procedure has been associated with a morbidity ranging from 1 to 20 per cent, depending largely on the patient population and the experience of the surgeon.
42,55,
105
106
107
108
109
Although many studies suggest that this procedure is effective in preventing additional TIAs or strokes,
55,
105
106
107
,
109
,
110
its value is yet to be confirmed by a well-designed, controlled, randomized clinical trial. In the one multicenter controlled study published thus far, 24 centers randomly assigned . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>6377062</pmid><doi>10.1056/NEJM198407123110206</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1984-07, Vol.311 (2), p.100-105 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; ProQuest Central UK/Ireland |
| subjects | Anticoagulants Anticoagulants - therapeutic use Arterial Occlusive Diseases - drug therapy Aspirin - therapeutic use Auscultation Basilar Artery Blood Platelets - drug effects Blood pressure Carotid arteries Carotid Arteries - physiopathology Carotid artery Carotid Artery Diseases - diagnosis Carotid Artery Diseases - therapy Cerebral Arteries - surgery Cerebrovascular Disorders - drug therapy Cerebrovascular Disorders - surgery Cerebrovascular Disorders - therapy Dipyridamole - therapeutic use Endarterectomy Heart surgery Humans Hypertension Intracranial Arteriosclerosis - complications Ischemia Ischemic Attack, Transient - drug therapy Medical imaging Morbidity Neurology Neurosurgery Patients Stroke Surgeons Ulcers Vascular diseases Veins & arteries Vertebral Artery |
| title | Therapy of Ischemic Cerebral Vascular Disease Due to Atherothrombosis |
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