Localization of aldosterone and corticosterone in the central nervous system, assessed by quantitative autoradiography

Nuclear localization of tritiated aldosterone in the CNS was studied in rats by numerical evaluation of silver grains, deposited over neuronal cell nuclei in thaw-mounted autoradiograms, and compared with the localization obtained after prior administration of a 100-fold excess of radioinert aldoste...

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Veröffentlicht in:	Neurochem. Res.; (United States) 1984-03, Vol.9 (3), p.333-350
Hauptverfasser:	BIRMINGHAM, M. K, SAR, M, STUMPF, W. E
Format:	Artikel
Sprache:	eng
Schlagworte:	550601 - Medicine- Unsealed Radionuclides in Diagnostics 551001 - Physiological Systems- Tracer Techniques ADRENAL HORMONES ALDEHYDES ALDOSTERONE Aldosterone - metabolism ANIMALS AUTORADIOGRAPHY BASIC BIOLOGICAL SCIENCES Biochemistry and metabolism Biological and medical sciences BIOLOGICAL LOCALIZATION Brain - drug effects Brain - metabolism Cell Nucleus - metabolism CENTRAL NERVOUS SYSTEM CORTICOSTEROIDS CORTICOSTERONE Corticosterone - metabolism Dihydrotestosterone - pharmacology Female Fundamental and applied biological sciences. Psychology GLUCOCORTICOIDS Hippocampus - metabolism HORMONES HYDROXY COMPOUNDS KETONES Kinetics LABELLED COMPOUNDS MAMMALS MINERALOCORTICOIDS NERVOUS SYSTEM ORGANIC COMPOUNDS PREGNANES Pyramidal Tracts - metabolism Radioisotope Dilution Technique RADIOLOGY AND NUCLEAR MEDICINE RADIONUCLIDE KINETICS RATS RECEPTORS RODENTS STEROID HORMONES STEROIDS Tritium TRITIUM COMPOUNDS VERTEBRATES Vertebrates: nervous system and sense organs
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