Primary lymphoma of the brain: A case report and review of the literature
A case of primary lymphoma of the brain is presented. The disease is rare and thus firm guidelines for therapy are lacking. Whole‐brain irradiation therapy, the accepted treatment of choice, when given to a dose of 5000 rads, is associated with improved survival. However, the overall prognosis is po...
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| Veröffentlicht in: | Journal of surgical oncology 1984-06, Vol.26 (2), p.115-121 |
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| container_end_page | 121 |
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| container_title | Journal of surgical oncology |
| container_volume | 26 |
| creator | Alic, Linda Haid, Max |
| description | A case of primary lymphoma of the brain is presented. The disease is rare and thus firm guidelines for therapy are lacking. Whole‐brain irradiation therapy, the accepted treatment of choice, when given to a dose of 5000 rads, is associated with improved survival. However, the overall prognosis is poor due to local recurrence in the central nervous system and the tumor's ability to diffusely infiltrate the meninges. Twenty‐six percent of the cases may have positive cerebrospinal fluid cytology. Whether the addition of intrathecal chemotherapy with agents such as methotrexate will improve upon the results obtained with irradiation therapy alone would be an appropriate subject for a cooperative prospective randomized study. |
| doi_str_mv | 10.1002/jso.2930260209 |
| format | Article |
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The disease is rare and thus firm guidelines for therapy are lacking. Whole‐brain irradiation therapy, the accepted treatment of choice, when given to a dose of 5000 rads, is associated with improved survival. However, the overall prognosis is poor due to local recurrence in the central nervous system and the tumor's ability to diffusely infiltrate the meninges. Twenty‐six percent of the cases may have positive cerebrospinal fluid cytology. Whether the addition of intrathecal chemotherapy with agents such as methotrexate will improve upon the results obtained with irradiation therapy alone would be an appropriate subject for a cooperative prospective randomized study.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930260209</identifier><identifier>PMID: 6738057</identifier><identifier>CODEN: JSONAU</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Biological and medical sciences ; brain ; Brain Neoplasms - drug therapy ; Brain Neoplasms - radiotherapy ; chemotherapy ; Cytarabine - therapeutic use ; cytology ; Female ; Hematologic and hematopoietic diseases ; Humans ; irradiation ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; lymphoma ; Lymphoma - drug therapy ; Lymphoma - radiotherapy ; Medical sciences ; Methotrexate - therapeutic use ; Middle Aged ; Neoplasm Recurrence, Local - radiotherapy ; Prognosis</subject><ispartof>Journal of surgical oncology, 1984-06, Vol.26 (2), p.115-121</ispartof><rights>Copyright © 1984 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4399-abadb0f1f305786f1ada0de581fe60ac346a7e8cee0bdb4a229a7abffa2b4e83</citedby><cites>FETCH-LOGICAL-c4399-abadb0f1f305786f1ada0de581fe60ac346a7e8cee0bdb4a229a7abffa2b4e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930260209$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930260209$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8906690$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6738057$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alic, Linda</creatorcontrib><creatorcontrib>Haid, Max</creatorcontrib><title>Primary lymphoma of the brain: A case report and review of the literature</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>A case of primary lymphoma of the brain is presented. The disease is rare and thus firm guidelines for therapy are lacking. Whole‐brain irradiation therapy, the accepted treatment of choice, when given to a dose of 5000 rads, is associated with improved survival. However, the overall prognosis is poor due to local recurrence in the central nervous system and the tumor's ability to diffusely infiltrate the meninges. Twenty‐six percent of the cases may have positive cerebrospinal fluid cytology. Whether the addition of intrathecal chemotherapy with agents such as methotrexate will improve upon the results obtained with irradiation therapy alone would be an appropriate subject for a cooperative prospective randomized study.</description><subject>Biological and medical sciences</subject><subject>brain</subject><subject>Brain Neoplasms - drug therapy</subject><subject>Brain Neoplasms - radiotherapy</subject><subject>chemotherapy</subject><subject>Cytarabine - therapeutic use</subject><subject>cytology</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>irradiation</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>lymphoma</subject><subject>Lymphoma - drug therapy</subject><subject>Lymphoma - radiotherapy</subject><subject>Medical sciences</subject><subject>Methotrexate - therapeutic use</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local - radiotherapy</subject><subject>Prognosis</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtP3DAQhy1UBMvjyg0ph6qcsh3HiWP3tqLlUSEeWiS4WZNkLALJZrGzhf3vMcqyqJf2NCPN95sZfYwdcBhzgOT7o-_GiRaQSEhAb7ARBy1jDVp9YaMAJHGaa9hmO94_AoDWMt1iWzIXCrJ8xM6vXd2iW0bNsp0_dC1GnY36B4oKh_XsRzSJSvQUOZp3ro9wVoX2T00vH1hT9-SwXzjaY5sWG0_7q7rLbk9-3R6fxRdXp-fHk4u4TIXWMRZYFWC5FeG-kpZjhVBRprglCViKVGJOqiSCoipSTBKNORbWYlKkpMQu-zasnbvueUG-N23tS2oanFG38EZxHnRIEcCjf4J5lmaSC80DOR7I0nXeO7JmPkgxHMy7ZBMkm0_JIXC4Wr0oWqrW-MpqmH9dzdGX2FiHs7L2a0xpkFJDwPSAvdQNLf9z1PyeXv31Qjxka9_T6zqL7un9izwzd5en5n6a_pxqdWJuxBvJDaTl</recordid><startdate>198406</startdate><enddate>198406</enddate><creator>Alic, Linda</creator><creator>Haid, Max</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>198406</creationdate><title>Primary lymphoma of the brain: A case report and review of the literature</title><author>Alic, Linda ; Haid, Max</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4399-abadb0f1f305786f1ada0de581fe60ac346a7e8cee0bdb4a229a7abffa2b4e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Biological and medical sciences</topic><topic>brain</topic><topic>Brain Neoplasms - drug therapy</topic><topic>Brain Neoplasms - radiotherapy</topic><topic>chemotherapy</topic><topic>Cytarabine - therapeutic use</topic><topic>cytology</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>irradiation</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>lymphoma</topic><topic>Lymphoma - drug therapy</topic><topic>Lymphoma - radiotherapy</topic><topic>Medical sciences</topic><topic>Methotrexate - therapeutic use</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local - radiotherapy</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alic, Linda</creatorcontrib><creatorcontrib>Haid, Max</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alic, Linda</au><au>Haid, Max</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary lymphoma of the brain: A case report and review of the literature</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1984-06</date><risdate>1984</risdate><volume>26</volume><issue>2</issue><spage>115</spage><epage>121</epage><pages>115-121</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><coden>JSONAU</coden><abstract>A case of primary lymphoma of the brain is presented. The disease is rare and thus firm guidelines for therapy are lacking. Whole‐brain irradiation therapy, the accepted treatment of choice, when given to a dose of 5000 rads, is associated with improved survival. However, the overall prognosis is poor due to local recurrence in the central nervous system and the tumor's ability to diffusely infiltrate the meninges. Twenty‐six percent of the cases may have positive cerebrospinal fluid cytology. 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| ispartof | Journal of surgical oncology, 1984-06, Vol.26 (2), p.115-121 |
| issn | 0022-4790 1096-9098 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Biological and medical sciences brain Brain Neoplasms - drug therapy Brain Neoplasms - radiotherapy chemotherapy Cytarabine - therapeutic use cytology Female Hematologic and hematopoietic diseases Humans irradiation Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis lymphoma Lymphoma - drug therapy Lymphoma - radiotherapy Medical sciences Methotrexate - therapeutic use Middle Aged Neoplasm Recurrence, Local - radiotherapy Prognosis |
| title | Primary lymphoma of the brain: A case report and review of the literature |
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