Informed consent for investigational chemotherapy: patients' and physicians' perceptions
One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent procedure, in which they participated one to three weeks earlier, for chemotherapy by one of 65 investigational protocols. Patients recalled the procedure positively and relied...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical oncology 1984-07, Vol.2 (7), p.849-855 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 855 |
|---|---|
| container_issue | 7 |
| container_start_page | 849 |
| container_title | Journal of clinical oncology |
| container_volume | 2 |
| creator | D T Penman J C Holland G F Bahna G Morrow A H Schmale L R Derogatis C L Carnrike, Jr R Cherry |
| description | One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent procedure, in which they participated one to three weeks earlier, for chemotherapy by one of 65 investigational protocols. Patients recalled the procedure positively and relied heavily on physician's advice. They felt most physicians wanted them to accept; 29% felt their participation in the decision was not encouraged. Primary reasons for accepting were trust in the physician, belief the treatment would help, and fear the disease (viewed as highly serious) would get worse without it. Nearly a fourth did not recall the information given that treatment was investigational. The consent form played no role in decision-making for 69%. Physicians believed therapeutic benefits would exceed potential problems for most patients; they viewed 41% of the patients as less than eager for details of treatment, a third as avoiding the seriousness of the discussion, and a third as passive in decision-making. The perceptual set of both parties places inadvertent constraint on patients' autonomy in decision making. |
| doi_str_mv | 10.1200/jco.1984.2.7.849 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81128464</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>81128464</sourcerecordid><originalsourceid>FETCH-LOGICAL-c389t-8e1da7a63b84d76525dd5d6e8c65c833010e60e858904172b64e0e2c560956853</originalsourceid><addsrcrecordid>eNo9kUlLA0EQhRtRYlzuXoQ5iJ5m7GV6GW8SXAnkopBb0-mpZDrMZvdEyb-3Q6KnoqreexRfIXRFcEYoxvdr22WkUHlGM5mpvDhCY8KpTKXk_BiNsWQ0JYrNT9FZCGuMSa4YH6GRkExiysZo_tYuO99AmdiuDdAOSWwT135DGNzKDK5rTZ3YCppuqMCbfvuQ9HEcleEuMW2Z9NU2OOtMG_sevIV-ZwoX6GRp6gCXh3qOPp-fPiav6XT28jZ5nKaWqWJIFZDSSCPYQuWlFJzysuSlAGUFt4oxTDAIDIqrAudE0oXIAQO1XOCCC8XZObrd5_a--9rEq3XjgoW6Ni10m6AVIVTlIo9CvBda34XgYal77xrjt5pgvYOp3yczvYOpqZY6woyW60P2ZhER_RsO9OL-Zr-v3Kr6cR50aExdRzXV8TN_Mb95Yn1S</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81128464</pqid></control><display><type>article</type><title>Informed consent for investigational chemotherapy: patients' and physicians' perceptions</title><source>MEDLINE</source><source>American Society of Clinical Oncology Online Journals</source><source>Journals@Ovid Complete</source><creator>D T Penman ; J C Holland ; G F Bahna ; G Morrow ; A H Schmale ; L R Derogatis ; C L Carnrike, Jr ; R Cherry</creator><creatorcontrib>D T Penman ; J C Holland ; G F Bahna ; G Morrow ; A H Schmale ; L R Derogatis ; C L Carnrike, Jr ; R Cherry</creatorcontrib><description>One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent procedure, in which they participated one to three weeks earlier, for chemotherapy by one of 65 investigational protocols. Patients recalled the procedure positively and relied heavily on physician's advice. They felt most physicians wanted them to accept; 29% felt their participation in the decision was not encouraged. Primary reasons for accepting were trust in the physician, belief the treatment would help, and fear the disease (viewed as highly serious) would get worse without it. Nearly a fourth did not recall the information given that treatment was investigational. The consent form played no role in decision-making for 69%. Physicians believed therapeutic benefits would exceed potential problems for most patients; they viewed 41% of the patients as less than eager for details of treatment, a third as avoiding the seriousness of the discussion, and a third as passive in decision-making. The perceptual set of both parties places inadvertent constraint on patients' autonomy in decision making.</description><identifier>ISSN: 0732-183X</identifier><identifier>EISSN: 1527-7755</identifier><identifier>DOI: 10.1200/jco.1984.2.7.849</identifier><identifier>PMID: 6737023</identifier><language>eng</language><publisher>United States: American Society of Clinical Oncology</publisher><subject>Adult ; Antineoplastic Agents - adverse effects ; Antineoplastic Agents - therapeutic use ; Bioethics ; Consent Forms ; Decision Making ; Female ; Human Experimentation - psychology ; Humans ; Informed Consent ; Interviews as Topic ; Male ; Middle Aged ; Neoplasms - drug therapy ; Patient Participation ; Patients - psychology ; Perception ; Physician's Role ; Physician-Patient Relations ; Physicians - psychology ; Risk Assessment ; Therapeutic Human Experimentation ; Trust</subject><ispartof>Journal of clinical oncology, 1984-07, Vol.2 (7), p.849-855</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-8e1da7a63b84d76525dd5d6e8c65c833010e60e858904172b64e0e2c560956853</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,3716,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6737023$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>D T Penman</creatorcontrib><creatorcontrib>J C Holland</creatorcontrib><creatorcontrib>G F Bahna</creatorcontrib><creatorcontrib>G Morrow</creatorcontrib><creatorcontrib>A H Schmale</creatorcontrib><creatorcontrib>L R Derogatis</creatorcontrib><creatorcontrib>C L Carnrike, Jr</creatorcontrib><creatorcontrib>R Cherry</creatorcontrib><title>Informed consent for investigational chemotherapy: patients' and physicians' perceptions</title><title>Journal of clinical oncology</title><addtitle>J Clin Oncol</addtitle><description>One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent procedure, in which they participated one to three weeks earlier, for chemotherapy by one of 65 investigational protocols. Patients recalled the procedure positively and relied heavily on physician's advice. They felt most physicians wanted them to accept; 29% felt their participation in the decision was not encouraged. Primary reasons for accepting were trust in the physician, belief the treatment would help, and fear the disease (viewed as highly serious) would get worse without it. Nearly a fourth did not recall the information given that treatment was investigational. The consent form played no role in decision-making for 69%. Physicians believed therapeutic benefits would exceed potential problems for most patients; they viewed 41% of the patients as less than eager for details of treatment, a third as avoiding the seriousness of the discussion, and a third as passive in decision-making. The perceptual set of both parties places inadvertent constraint on patients' autonomy in decision making.</description><subject>Adult</subject><subject>Antineoplastic Agents - adverse effects</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Bioethics</subject><subject>Consent Forms</subject><subject>Decision Making</subject><subject>Female</subject><subject>Human Experimentation - psychology</subject><subject>Humans</subject><subject>Informed Consent</subject><subject>Interviews as Topic</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasms - drug therapy</subject><subject>Patient Participation</subject><subject>Patients - psychology</subject><subject>Perception</subject><subject>Physician's Role</subject><subject>Physician-Patient Relations</subject><subject>Physicians - psychology</subject><subject>Risk Assessment</subject><subject>Therapeutic Human Experimentation</subject><subject>Trust</subject><issn>0732-183X</issn><issn>1527-7755</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kUlLA0EQhRtRYlzuXoQ5iJ5m7GV6GW8SXAnkopBb0-mpZDrMZvdEyb-3Q6KnoqreexRfIXRFcEYoxvdr22WkUHlGM5mpvDhCY8KpTKXk_BiNsWQ0JYrNT9FZCGuMSa4YH6GRkExiysZo_tYuO99AmdiuDdAOSWwT135DGNzKDK5rTZ3YCppuqMCbfvuQ9HEcleEuMW2Z9NU2OOtMG_sevIV-ZwoX6GRp6gCXh3qOPp-fPiav6XT28jZ5nKaWqWJIFZDSSCPYQuWlFJzysuSlAGUFt4oxTDAIDIqrAudE0oXIAQO1XOCCC8XZObrd5_a--9rEq3XjgoW6Ni10m6AVIVTlIo9CvBda34XgYal77xrjt5pgvYOp3yczvYOpqZY6woyW60P2ZhER_RsO9OL-Zr-v3Kr6cR50aExdRzXV8TN_Mb95Yn1S</recordid><startdate>198407</startdate><enddate>198407</enddate><creator>D T Penman</creator><creator>J C Holland</creator><creator>G F Bahna</creator><creator>G Morrow</creator><creator>A H Schmale</creator><creator>L R Derogatis</creator><creator>C L Carnrike, Jr</creator><creator>R Cherry</creator><general>American Society of Clinical Oncology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198407</creationdate><title>Informed consent for investigational chemotherapy: patients' and physicians' perceptions</title><author>D T Penman ; J C Holland ; G F Bahna ; G Morrow ; A H Schmale ; L R Derogatis ; C L Carnrike, Jr ; R Cherry</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-8e1da7a63b84d76525dd5d6e8c65c833010e60e858904172b64e0e2c560956853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adult</topic><topic>Antineoplastic Agents - adverse effects</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Bioethics</topic><topic>Consent Forms</topic><topic>Decision Making</topic><topic>Female</topic><topic>Human Experimentation - psychology</topic><topic>Humans</topic><topic>Informed Consent</topic><topic>Interviews as Topic</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasms - drug therapy</topic><topic>Patient Participation</topic><topic>Patients - psychology</topic><topic>Perception</topic><topic>Physician's Role</topic><topic>Physician-Patient Relations</topic><topic>Physicians - psychology</topic><topic>Risk Assessment</topic><topic>Therapeutic Human Experimentation</topic><topic>Trust</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>D T Penman</creatorcontrib><creatorcontrib>J C Holland</creatorcontrib><creatorcontrib>G F Bahna</creatorcontrib><creatorcontrib>G Morrow</creatorcontrib><creatorcontrib>A H Schmale</creatorcontrib><creatorcontrib>L R Derogatis</creatorcontrib><creatorcontrib>C L Carnrike, Jr</creatorcontrib><creatorcontrib>R Cherry</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>D T Penman</au><au>J C Holland</au><au>G F Bahna</au><au>G Morrow</au><au>A H Schmale</au><au>L R Derogatis</au><au>C L Carnrike, Jr</au><au>R Cherry</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Informed consent for investigational chemotherapy: patients' and physicians' perceptions</atitle><jtitle>Journal of clinical oncology</jtitle><addtitle>J Clin Oncol</addtitle><date>1984-07</date><risdate>1984</risdate><volume>2</volume><issue>7</issue><spage>849</spage><epage>855</epage><pages>849-855</pages><issn>0732-183X</issn><eissn>1527-7755</eissn><abstract>One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent procedure, in which they participated one to three weeks earlier, for chemotherapy by one of 65 investigational protocols. Patients recalled the procedure positively and relied heavily on physician's advice. They felt most physicians wanted them to accept; 29% felt their participation in the decision was not encouraged. Primary reasons for accepting were trust in the physician, belief the treatment would help, and fear the disease (viewed as highly serious) would get worse without it. Nearly a fourth did not recall the information given that treatment was investigational. The consent form played no role in decision-making for 69%. Physicians believed therapeutic benefits would exceed potential problems for most patients; they viewed 41% of the patients as less than eager for details of treatment, a third as avoiding the seriousness of the discussion, and a third as passive in decision-making. The perceptual set of both parties places inadvertent constraint on patients' autonomy in decision making.</abstract><cop>United States</cop><pub>American Society of Clinical Oncology</pub><pmid>6737023</pmid><doi>10.1200/jco.1984.2.7.849</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0732-183X |
| ispartof | Journal of clinical oncology, 1984-07, Vol.2 (7), p.849-855 |
| issn | 0732-183X 1527-7755 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81128464 |
| source | MEDLINE; American Society of Clinical Oncology Online Journals; Journals@Ovid Complete |
| subjects | Adult Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Bioethics Consent Forms Decision Making Female Human Experimentation - psychology Humans Informed Consent Interviews as Topic Male Middle Aged Neoplasms - drug therapy Patient Participation Patients - psychology Perception Physician's Role Physician-Patient Relations Physicians - psychology Risk Assessment Therapeutic Human Experimentation Trust |
| title | Informed consent for investigational chemotherapy: patients' and physicians' perceptions |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T17%3A11%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Informed%20consent%20for%20investigational%20chemotherapy:%20patients'%20and%20physicians'%20perceptions&rft.jtitle=Journal%20of%20clinical%20oncology&rft.au=D%20T%20Penman&rft.date=1984-07&rft.volume=2&rft.issue=7&rft.spage=849&rft.epage=855&rft.pages=849-855&rft.issn=0732-183X&rft.eissn=1527-7755&rft_id=info:doi/10.1200/jco.1984.2.7.849&rft_dat=%3Cproquest_cross%3E81128464%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81128464&rft_id=info:pmid/6737023&rfr_iscdi=true |