Relation of epidermal growth factor receptor concentration to growth of human epidermoid carcinoma A431 cells

The relation between the concentration of epidermal growth factor (EGF) receptor/kinase and effects of EGF on cell proliferation has been studied using variant A431 cells and antagonist anti-EGF receptor monoclonal antibodies. Clonal A431 cell variants selected for escape from the EGF-mediated growt...

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Veröffentlicht in:	The Journal of biological chemistry 1984-06, Vol.259 (12), p.7761-7766
Hauptverfasser:	Kawamoto, T, Mendelsohn, J, Le, A, Sato, G H, Lazar, C S, Gill, G N
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Biological and medical sciences Carcinoma, Squamous Cell - metabolism Cell Division Cell Line Cell physiology ErbB Receptors Fundamental and applied biological sciences. Psychology Humans Molecular and cellular biology Protein Kinases - metabolism Protein-Tyrosine Kinases Receptors, Cell Surface - metabolism Responses to growth factors, tumor promotors, other factors
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