Lack of influence of beta adrenergic blockade on serum potassium during an infusion of potassium
The extent to which the serum potassium rose in a group of six healthy volunteers during an intra-venous infusion of potassium was identical following pretreatment with placebo, low or high dose propranolol and low or high dose metoprolol. Thus in this acute study, we were unable to demonstrate any...
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| Veröffentlicht in: | European journal of clinical pharmacology 1984-01, Vol.26 (4), p.425-427 |
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| container_end_page | 427 |
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| container_issue | 4 |
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| container_title | European journal of clinical pharmacology |
| container_volume | 26 |
| creator | ROLF SMITH, S KENDALL, M. J RYDER, C LAUGHER, S |
| description | The extent to which the serum potassium rose in a group of six healthy volunteers during an intra-venous infusion of potassium was identical following pretreatment with placebo, low or high dose propranolol and low or high dose metoprolol. Thus in this acute study, we were unable to demonstrate any influence of either selective or non-selective beta adrenergic blockade upon potassium uptake mechanisms. This is in contrast to the effects of beta blockers on potassium reuptake rates noted after exercise and during cardiac surgery. |
| doi_str_mv | 10.1007/BF00542135 |
| format | Article |
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This is in contrast to the effects of beta blockers on potassium reuptake rates noted after exercise and during cardiac surgery.</description><identifier>ISSN: 0031-6970</identifier><identifier>EISSN: 1432-1041</identifier><identifier>DOI: 10.1007/BF00542135</identifier><identifier>PMID: 6329768</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Adult ; Biological and medical sciences ; Cardiovascular system ; Homeostasis - drug effects ; Humans ; Infusions, Parenteral ; Male ; Medical sciences ; Metoprolol - administration & dosage ; Metoprolol - pharmacology ; Miscellaneous ; Pharmacology. 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J</creatorcontrib><creatorcontrib>RYDER, C</creatorcontrib><creatorcontrib>LAUGHER, S</creatorcontrib><title>Lack of influence of beta adrenergic blockade on serum potassium during an infusion of potassium</title><title>European journal of clinical pharmacology</title><addtitle>Eur J Clin Pharmacol</addtitle><description>The extent to which the serum potassium rose in a group of six healthy volunteers during an intra-venous infusion of potassium was identical following pretreatment with placebo, low or high dose propranolol and low or high dose metoprolol. Thus in this acute study, we were unable to demonstrate any influence of either selective or non-selective beta adrenergic blockade upon potassium uptake mechanisms. This is in contrast to the effects of beta blockers on potassium reuptake rates noted after exercise and during cardiac surgery.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Homeostasis - drug effects</subject><subject>Humans</subject><subject>Infusions, Parenteral</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metoprolol - administration & dosage</subject><subject>Metoprolol - pharmacology</subject><subject>Miscellaneous</subject><subject>Pharmacology. Drug treatments</subject><subject>Potassium - administration & dosage</subject><subject>Potassium - blood</subject><subject>Propranolol - administration & dosage</subject><subject>Propranolol - pharmacology</subject><subject>Receptors, Adrenergic, beta - drug effects</subject><issn>0031-6970</issn><issn>1432-1041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkT1PwzAQhi0EKqWwsCNlQAxIAV-cxPYIFQWkSiwwh4tzrkLzUexk4N_jiqhMPut99Ej3HmOXwO-Ac3n_uOI8SxMQ2RGbQyqSGHgKx2zOuYA415KfsjPvvziHTHMxY7NcJFrmas4-12i2UW-jurPNSJ2h_aekASOsHHXkNrWJyqY3W6xC1kWe3NhGu35A7-swVaOru02E3V4x-jogwXDIz9mJxcbTxfQu2Mfq6X35Eq_fnl-XD-vYCIAhRq0ArMwMr0prpa0AUiBFKhdlgkpUlCbWoMSErFKmLEvUYWOkVGuVVlIs2M2fd-f675H8ULS1N9Q02FE_-iLoQScSAnj7BxrXe-_IFjtXt-h-CuDFvs7iv84AX03WsWypOqBTfyG_nnL0BhvrsDO1P2BKZUqHg_wCCbd9Sw</recordid><startdate>19840101</startdate><enddate>19840101</enddate><creator>ROLF SMITH, S</creator><creator>KENDALL, M. 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Drug treatments</topic><topic>Potassium - administration & dosage</topic><topic>Potassium - blood</topic><topic>Propranolol - administration & dosage</topic><topic>Propranolol - pharmacology</topic><topic>Receptors, Adrenergic, beta - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ROLF SMITH, S</creatorcontrib><creatorcontrib>KENDALL, M. 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This is in contrast to the effects of beta blockers on potassium reuptake rates noted after exercise and during cardiac surgery.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>6329768</pmid><doi>10.1007/BF00542135</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0031-6970 |
| ispartof | European journal of clinical pharmacology, 1984-01, Vol.26 (4), p.425-427 |
| issn | 0031-6970 1432-1041 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Adult Biological and medical sciences Cardiovascular system Homeostasis - drug effects Humans Infusions, Parenteral Male Medical sciences Metoprolol - administration & dosage Metoprolol - pharmacology Miscellaneous Pharmacology. Drug treatments Potassium - administration & dosage Potassium - blood Propranolol - administration & dosage Propranolol - pharmacology Receptors, Adrenergic, beta - drug effects |
| title | Lack of influence of beta adrenergic blockade on serum potassium during an infusion of potassium |
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