Comparison of rat and human left ventricle beta-adrenergic receptors: Subtype heterogeneity delineated by direct radioligand binding

Beta adrenergic receptors were identified in rat myocardial left ventricle and human papillary muscle by using the antagonist radioligand 3H-dihydroalprenolol. The number (37.3 and 44.5 fmol/mg of protein, respectively in rat and man), and the K D (1.6 and 2.8 nM, respectively in rat and man) of bet...

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Veröffentlicht in:	Biochemical and biophysical research communications 1984-05, Vol.121 (1), p.346-354
Hauptverfasser:	Vago, Tarcisio, Bevilacqua, Maurizio, Dagani, Regina, Meroni, Rachele, Frigeni, Giulio, Santoli, Carmine, Norbiato, Guido
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals beta -adrenergic Binding, Competitive Cell Membrane - metabolism Dihydroalprenolol - metabolism Female Humans Male man Middle Aged Myocardium - metabolism Protein Binding Radioligand Assay Rats Rats, Inbred Strains Receptors, Adrenergic, beta - classification Receptors, Adrenergic, beta - metabolism Species Specificity ventricle
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