Renin and the Complications of Acute Myocardial Infarction
To determine whether plasma renin activity in addition to catecholamines could be used as risk indicators, these parameters were measured in 19 patients with acute myocardial infarction. During the course of hospitalization, five patients developed ventricular fibrillation and three, cardiogenic sho...
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Veröffentlicht in: | Chest 1984-07, Vol.86 (1), p.40-43 |
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creator | Vaney, C. Waeber, B. Turini, G. Margalith, D. Brunner, H.R. Perret, C. |
description | To determine whether plasma renin activity in addition to catecholamines could be used as risk indicators, these parameters were measured in 19 patients with acute myocardial infarction. During the course of hospitalization, five patients developed ventricular fibrillation and three, cardiogenic shock. On admission, heart rate, plasma norepinephrine, epinephrine, and renin levels of these eight patients were significantly higher than those of the other patients with uncomplicated course. Peak creatine kinase MB activity was positively related to initial plasma renin activity (r=0.62, p |
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During the course of hospitalization, five patients developed ventricular fibrillation and three, cardiogenic shock. On admission, heart rate, plasma norepinephrine, epinephrine, and renin levels of these eight patients were significantly higher than those of the other patients with uncomplicated course. Peak creatine kinase MB activity was positively related to initial plasma renin activity (r=0.62, p<0.01). Thus, the patients with the highest sympathetic activity following an acute myocardial infarction also had the highest plasma renin levels. They seem particularly prone to develop large infarcts and life-threatening complications.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.86.1.40</identifier><identifier>PMID: 6375989</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Acute Disease ; Aged ; Biological and medical sciences ; Blood Pressure ; Cardiology. 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During the course of hospitalization, five patients developed ventricular fibrillation and three, cardiogenic shock. On admission, heart rate, plasma norepinephrine, epinephrine, and renin levels of these eight patients were significantly higher than those of the other patients with uncomplicated course. Peak creatine kinase MB activity was positively related to initial plasma renin activity (r=0.62, p<0.01). Thus, the patients with the highest sympathetic activity following an acute myocardial infarction also had the highest plasma renin levels. They seem particularly prone to develop large infarcts and life-threatening complications.</description><subject>Acute Disease</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure</subject><subject>Cardiology. Vascular system</subject><subject>Catecholamines - blood</subject><subject>Coronary heart disease</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - blood</subject><subject>Renin - blood</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM1v1DAQxS1EVZbCkSNSDohbth47m9jcqhUflYoqIThbsxObdeXYi50U9b9vthuVEyfLer95b-Yx9g74GmSnLmlvy7hW7RrWDX_BVqAl1HLTyJdsxTmIWrZavGKvS7nj8x90e87OW9lttNIr9umHjT5WGPtq3Ntqm4ZD8ISjT7FUyVVXNI22-v6QCHPvMVTX0WGmo_6GnTkMxb5d3gv268vnn9tv9c3t1-vt1U1NDZdjTXIndug63lutAYVohBLoCJwTupPA5ytIKVCdFT3Xjrek5abHViu5k6DkBft48j3k9GeajzWDL2RDwGjTVIwCACE6PoP1CaScSsnWmUP2A-YHA9wcuzJPXRnVGjDNkX-_GE-7wfbP9FLOrH9YdCyEwWWM5MszptuOi6f9lti9_73_67M1ZcAQZlN5CrxLU44Y_sV2J97Opd17m00hbyPZfp6l0fTJ_2fhR3LBlK4</recordid><startdate>198407</startdate><enddate>198407</enddate><creator>Vaney, C.</creator><creator>Waeber, B.</creator><creator>Turini, G.</creator><creator>Margalith, D.</creator><creator>Brunner, H.R.</creator><creator>Perret, C.</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198407</creationdate><title>Renin and the Complications of Acute Myocardial Infarction</title><author>Vaney, C. ; Waeber, B. ; Turini, G. ; Margalith, D. ; Brunner, H.R. ; Perret, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-c3b2baf70de991a224282afc1ff297310137c88187e2d09f06c935da6983b3183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Acute Disease</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure</topic><topic>Cardiology. Vascular system</topic><topic>Catecholamines - blood</topic><topic>Coronary heart disease</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Rate</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - blood</topic><topic>Renin - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaney, C.</creatorcontrib><creatorcontrib>Waeber, B.</creatorcontrib><creatorcontrib>Turini, G.</creatorcontrib><creatorcontrib>Margalith, D.</creatorcontrib><creatorcontrib>Brunner, H.R.</creatorcontrib><creatorcontrib>Perret, C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaney, C.</au><au>Waeber, B.</au><au>Turini, G.</au><au>Margalith, D.</au><au>Brunner, H.R.</au><au>Perret, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Renin and the Complications of Acute Myocardial Infarction</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>1984-07</date><risdate>1984</risdate><volume>86</volume><issue>1</issue><spage>40</spage><epage>43</epage><pages>40-43</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>To determine whether plasma renin activity in addition to catecholamines could be used as risk indicators, these parameters were measured in 19 patients with acute myocardial infarction. During the course of hospitalization, five patients developed ventricular fibrillation and three, cardiogenic shock. On admission, heart rate, plasma norepinephrine, epinephrine, and renin levels of these eight patients were significantly higher than those of the other patients with uncomplicated course. Peak creatine kinase MB activity was positively related to initial plasma renin activity (r=0.62, p<0.01). Thus, the patients with the highest sympathetic activity following an acute myocardial infarction also had the highest plasma renin levels. They seem particularly prone to develop large infarcts and life-threatening complications.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>6375989</pmid><doi>10.1378/chest.86.1.40</doi><tpages>4</tpages></addata></record> |
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subjects | Acute Disease Aged Biological and medical sciences Blood Pressure Cardiology. Vascular system Catecholamines - blood Coronary heart disease Female Heart Heart Rate Humans Male Medical sciences Middle Aged Myocardial Infarction - blood Renin - blood |
title | Renin and the Complications of Acute Myocardial Infarction |
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